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NCT04803305 · ClinicalTrials.gov registry record · Phase 1
Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
A Phase 1 study of Breast Cancer and Prostate Cancer, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 20
- Study locations
NCT04803305: Completed Phase 1 study of Breast Cancer and Prostate Cancer, sponsored by Pfizer.
NCT04803305 is a Phase 1 study of Breast Cancer and Prostate Cancer that has completed, run by Pfizer. The registered enrollment target is 18 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04803305, a Phase 1 study of Breast Cancer and Prostate Cancer, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 20
- Study locations
Study Summary
Study to compare the effects of the investigational new drug (PF-06946860) and a placebo on appetite and to find out how participants with advanced cancer and anorexia feel after receiving repeated subcutaneous (SC-injected under the skin) doses.
Primary Outcome
The Cancer-Related Cachexia Symptom Assessment-Appetite was a self-reported questionnaire that measured the severity of anorexia. The measure consisted of 1 question that asked study participants to rate their appetite over the past 7 days from 0-"no appetite" to 10-"very good appetite", where higher score indicated better appetite. In this Outcome Measure (OM), changes from baseline in the Cancer-Related Cachexia Symptom Assessment-Appetite score at Week 4 were summarized descriptively by trea
Conditions Studied
Interventions
- DRUG PF-06946860
- DRUG Placebo for PF-06946860
Study Locations (20)
California
- Tower Hematology Oncology Medical Group (THO) - Beverly Hills
- Ventura County Hematology- Oncology Specialists - Camarillo
- Cedars- Sinai Medical Center - Los Angeles
- Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute - Los Angeles
- Cedars-Sinai Medical Center - Los Angeles
- Ventura County Hematology Oncology Specialists - Oxnard
- Providence Medical Foundation - Santa Rosa
- Ventura County Hematology-Oncology Specialists - Ventura
Texas
- Mary Crowley Cancer Research - Dallas
- The University of Texas MD Anderson Cancer Center - Houston
- US Oncology Investigational Product Center (IPC) - Irving
- Texas Oncology - Longview Cancer Center - Longview
- Texas Oncology-Paris - Paris
- Texas Oncology- Tyler - Tyler
Montana
- Bozeman Health Cancer Center - Bozeman
- Bozeman Health Deaconess Hospital d/b/a Bozeman Health Clinical Research - Bozeman
- Bozeman Health Deaconess Hospital - Bozeman
Arkansas
- CARTI Cancer Center - Little Rock
Colorado
- Lutheran Medical Center - Wheat Ridge
Indiana
- Fort Wayne Medical Oncology and Hematology, Inc. - Fort Wayne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2021-05-11 |
| Est. Completion | 2022-08-09 |
| Phase | Phase 1 |
What the finished NCT04803305 record still lists
NCT04803305 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which PF-06946860 is the first listed.
NCT04803305 names 20 study sites across 6 states, led by California, Texas, Montana.
Frequently Asked Questions
What is clinical trial NCT04803305 about?
NCT04803305 is a clinical study titled "Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia". Study to compare the effects of the investigational new drug (PF-06946860) and a placebo on appetite and to find out how participants with advanced cancer and anorexia feel after receiving repeated subcutaneous (SC-injected under the skin) doses.
What is the current status of trial NCT04803305?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2021-05-11. Estimated completion is 2022-08-09.
What conditions does trial NCT04803305 study?
This clinical trial studies the following conditions: Breast Cancer, Prostate Cancer, Non-Small Cell Lung Cancer, Colorectal Cancer, Ovarian Cancer.
What interventions are being tested in trial NCT04803305?
The interventions under investigation include: PF-06946860 (DRUG), Placebo for PF-06946860 (DRUG).
Who is sponsoring clinical trial NCT04803305?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04803305 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Indiana, Montana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT04803305's enrollment target sits among peer trials
18 1118th of 1224 higher than 97 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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