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NCT01950403 · ClinicalTrials.gov registry record · Phase 1

Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers

A Phase 1 study of Colorectal Cancer and Healthy, no Evidence of Disease, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target
1
Study location

NCT01950403 is a Phase 1 study of Colorectal Cancer and Healthy, no Evidence of Disease that has completed, run by Mayo Clinic. The registered enrollment target is 24 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01950403, a Phase 1 study of Colorectal Cancer and Healthy, no Evidence of Disease, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

This randomized phase I trial studies the side effects and best dose of linaclotide acetate in preventing colorectal cancer in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of linaclotide acetate may prevent colorectal cancer.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER placebo
  • OTHER pharmacological study
  • DRUG linaclotide acetate

Study Locations (1)

Pennsylvania

  • Thomas Jefferson University - Philadelphia

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-09
Est. Completion 2018-02-22
Phase Phase 1

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT01950403

The ClinicalTrials.gov registry entry for NCT01950403 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT01950403 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT01950403 about?

NCT01950403 is a clinical study titled "Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers". This randomized phase I trial studies the side effects and best dose of linaclotide acetate in preventing colorectal cancer in healthy volunteers. Chemoprevention is the use of certain drugs to keep cancer from forming. The use of linaclotide acetate may prevent colorectal cancer.

What is the current status of trial NCT01950403?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2013-09. Estimated completion is 2018-02-22.

What conditions does trial NCT01950403 study?

This clinical trial studies the following conditions: Colorectal Cancer, Healthy, no Evidence of Disease.

What interventions are being tested in trial NCT01950403?

The interventions under investigation include: laboratory biomarker analysis (OTHER), placebo (OTHER), pharmacological study (OTHER), linaclotide acetate (DRUG).

Who is sponsoring clinical trial NCT01950403?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01950403 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.