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NCT01874860 · ClinicalTrials.gov registry record · Phase 2

Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients

A Phase 2 study of Colorectal Cancer and Head and Neck Cancer, sponsored by University of Louisville.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target
1
Study location

NCT01874860: Completed Phase 2 study of Colorectal Cancer and Head and Neck Cancer, sponsored by University of Louisville.

NCT01874860 is a Phase 2 study of Colorectal Cancer and Head and Neck Cancer that has completed, run by University of Louisville. The registered enrollment target is 24 participants, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01874860, a Phase 2 study of Colorectal Cancer and Head and Neck Cancer, has completed, sponsored by University of Louisville.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine if using preventive treatments such as Doxycycline (an anti-biotic) capsules, sunscreen with SPF 30, Hydrocortisone 1% cream and a moisturizer will help to reduce the incidence and severity of the skin rash associated with Cetuximab (Erbitux®) when compared to receiving standard care for the treatment of skin rash.

Primary Outcome

Evaluate the incidence of cetuximab-induced rash, Compare the severity of cetuximab-induced rash between the extensive treatment group (ETG) and the standard care group (SCG).

Interventions

  • DRUG Clindamycin
  • DRUG Doxycycline
  • OTHER Sunscreen
  • DRUG Hydrocortisone 1% cream
  • OTHER Moisturizer

Study Locations (1)

Kentucky

  • James Graham Brown Cancer Center - Louisville

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-08
Est. Completion 2018-07
Phase Phase 2
University of Louisville

217 total trials

What the finished NCT01874860 record still lists

NCT01874860 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,545-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 5 interventions - of which Clindamycin is the first listed.

NCT01874860 reports a single indexed study location in Kentucky.

Frequently Asked Questions

What is clinical trial NCT01874860 about?

NCT01874860 is a clinical study titled "Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients". The purpose of this study is to determine if using preventive treatments such as Doxycycline (an anti-biotic) capsules, sunscreen with SPF 30, Hydrocortisone 1% cream and a moisturizer will help to reduce the incidence and severity of the skin rash associated with Cetuximab (Erbitux®) when compared ...

What is the current status of trial NCT01874860?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2013-08. Estimated completion is 2018-07.

What conditions does trial NCT01874860 study?

This clinical trial studies the following conditions: Colorectal Cancer, Head and Neck Cancer.

What interventions are being tested in trial NCT01874860?

The interventions under investigation include: Clindamycin (DRUG), Doxycycline (DRUG), Sunscreen (OTHER), Hydrocortisone 1% cream (DRUG), Moisturizer (OTHER).

Who is sponsoring clinical trial NCT01874860?

This trial is sponsored by University of Louisville, which has 217 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01874860 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Colorectal Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01874860's enrollment target sits among peer trials

24 333rd of 381 higher than 44 of 381 other Colorectal Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01874860, the US trial registry maintained by the National Library of Medicine. NCT01874860 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.