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Breast Neoplasms clinical trials
35 of 98 indexed Breast Neoplasms trials are currently recruiting.
98 US clinical trials · 35 currently recruiting
Breast Neoplasms is the subject of 98 registered US clinical trials on ClinicalTrials.gov, 35 of them currently open to new participants. 20 are in Phase 3-4 (later-stage) and 51 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 10 of these trials.
The research picture
Breast Neoplasms has 98 registered US clinical trials, 35 of them open to new participants right now, about 36% of the total.
- 35
- recruiting participants now
- 36%
- of trials open to enrollment
- 20
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Pfizer
Active & Recent Trials
98 total, page 2 of 2
A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations
Atavistik Bio
NCT07038369
Multi-Institutional Transgender & Gender-Diverse Breast Cancer Study
Medical College of Wisconsin
NCT06234488
PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer
Washington University School of Medicine
NCT01723774
Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy
Memorial Sloan Kettering Cancer Center
NCT04769960
Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast
Icahn School of Medicine at Mount Sinai
NCT03304080
Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer
City of Hope Medical Center
NCT01273610
Trial of Ibrutinib Plus Trastuzumab in HER2-amplified Metastatic Breast Cancer
US Oncology Research
NCT03379428
A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
Eisai
NCT04288089
Pembrolizumab, IRX-2, and Chemotherapy in Triple Negative Breast Cancer
Providence Health & Services
NCT04373031
Raloxifene Use for The Heart
Eli Lilly and Company
NCT00190593
A Study to Understand About the Study Medicine Palbociclib in Breast Cancer Patients After it is Out in the Japanese Market
Pfizer
NCT07096024
Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer
Intarcia Therapeutics
NCT00044291
Study Of Sunitinib In Combination With Docetaxel Vs Docetaxel In Patients With Advanced Breast Cancer
Pfizer
NCT00393939
A Study Of SU011248 Plus Paclitaxel Versus Bevacizumab Plus Paclitaxel In Patients With Advanced Breast Cancer
Pfizer
NCT00373256
A Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Hoffmann-La Roche
NCT02131064
A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study)
Pfizer
NCT01945775
A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer Patients
Washington University School of Medicine
NCT00355316
Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
Icahn School of Medicine at Mount Sinai
NCT02657993
AG-013736 In Combination With Docetaxel Versus Docetaxel Alone For Patients With Metastatic Breast Cancer
Pfizer
NCT00076024
Nuevo Amanecer: Promoting the Psychosocial Health of Latinas
University of California, San Francisco
NCT01383174
A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer
Hoffmann-La Roche
NCT03280563
This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer
Boehringer Ingelheim
NCT03099174
Contrast Enhanced Mammography in Diagnosing Patients With Suspicious Breast Findings
Thomas Jefferson University
NCT03929783
A Dose-escalation, Expansion Study of ARX788, in Advanced Solid Tumors Subjects With HER2 Expression (ACE-Pan Tumor 01)
Ambrx
NCT03255070
Testing of Different Methods for Determining Whether Breast Cancer Has Spread to the Lymph Nodes
Washington University School of Medicine
NCT00360152
Efficacy Study of an Educational Program for Decision Support for Breast Cancer
Baylor College of Medicine
NCT00473096
Study Of The Efficacy And Safety Of SU-014813 In Patients With Metastatic Breast Cancer
Pfizer
NCT00322517
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Novartis Pharmaceuticals
NCT02077933
Bevacizumab Given With Either Anastrozole or Fulvestrant With Trastuzumab for Postmenopausal Metastatic Breast Cancer
SCRI Development Innovations
NCT00405938
Evaluating and Comparing Two Surgical Methods for Treatment of Early Stage Breast Cancer
Emory University
NCT01271738
Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity
University of Texas Southwestern Medical Center
NCT03685175
Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor-Associated Vasculature in Patients With Metastatic Breast Cancer
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00071357
A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy With GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer
National Cancer Institute (NCI)
NCT00001338
Phase 2 Study of TLK286 in Metastatic Breast Cancer
Telik
NCT00035841
Vaccination of High Risk Breast Cancer Patients
University of Arkansas
NCT02229084
Exemestane and Celecoxib in Postmenopausal Women at High Risk for Breast Cancer
Georgetown University
NCT00073073
Study of XL147 (SAR245408) in Combination With Trastuzumab or Paclitaxel and Trastuzumab in Subjects With Metastatic Breast Cancer Who Have Progressed on a Previous Trastuzumab-based Regimen
Sanofi
NCT01042925
Enzastaurin For Breast Cancer Patients Who Previously Received an Anthracycline and a Taxane Chemotherapy
Eli Lilly and Company
NCT00386087
Know Your Risk: Assessment at Screening for Breast Cancer - Pilot Study
Columbia University
NCT02954900
Treatment Patterns and Clinical Outcomes Among Talazoparib-Treated Adults With HER2-Negative mBC With gBRCA1/2m
Pfizer
NCT05141708
PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)
Pfizer
NCT00043368
Phase II Study to Evaluate Tariquidar (XR9576), a Selective MDR-1 Inhibitor, in Chemotherapy Resistant Advanced Breast Cancer
QLT
NCT00048633
Afatinib (BIBW2992) in HER2 (Human Epidermal Growth Factor Receptor 2)-Overexpressing Inflammatory Breast Cancer
Boehringer Ingelheim
NCT01325428
Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer
Pharmacyclics
NCT00120939
Ultrasound Targeting for the Lumpectomy Cavity
University of Iowa
NCT00583843
Bright Light on Fatigue in Women Being Treated for Breast Cancer
Washington University School of Medicine
NCT02658708
Studying Normal Breast Tissue and Cancer Risk
National Cancer Institute (NCI)
NCT00341692
Evaluating the T Cell Response to a Peptide-based Vaccine in Patients With Breast Cancer
Craig L Slingluff, Jr
NCT00892567
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 22 |
| Phase 3 | 19 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Breast Neoplasms Trial Landscape
98 indexed Breast Neoplasms studies · 35 recruiting (36%).
Phase mix: 20 late (III/IV) vs 51 early (I/II).
Top sponsor: Pfizer (10 trials), 9 others listed. 48 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Breast Neoplasms?
PlainTrial tracks 98 US clinical trials for Breast Neoplasms, of which 35 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Breast Neoplasms?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.