Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 1

AG-013736 In Combination With Docetaxel Versus Docetaxel Alone For Patients With Metastatic Breast Cancer

NCT00076024 · View on ClinicalTrials.gov ↗

Study Summary

The primary purpose of the study is to determine the time to progression of the combination of study drug (AG-013736) and docetaxel versus docetaxel alone in patients who have not received prior chemotherapy for metastatic breast cancer. The secondary purpose of the study is to determine the dose of study drug that can be given with docetaxel administered on an every 3 week schedule.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Docetaxel
  • DRUG AG-013736 (axitinib)

Study Locations (20)

Florida

  • Pfizer Investigational Site — Jacksonville
  • Pfizer Investigational Site — Jacksonville
  • Pfizer Investigational Site — Jacksonville
  • Pfizer Investigational Site — Jacksonville Beach
  • Pfizer Investigational Site — Melbourne
  • Pfizer Investigational Site — Orange Park
  • Pfizer Investigational Site — Palatka
  • Pfizer Investigational Site — Saint Augustine

California

  • Pfizer Investigational Site — Berkeley
  • Pfizer Investigational Site — Montebello
  • Pfizer Investigational Site — Monterey Park
  • Pfizer Investigational Site — San Francisco
  • Pfizer Investigational Site — San Gabriel
  • Pfizer Investigational Site — Whittier

Illinois

  • Pfizer Investigational Site — Chicago
  • Pfizer Investigational Site — Chicago
  • Pfizer Investigational Site — Zion

Arizona

  • Pfizer Investigational Site — Tucson
  • Pfizer Investigational Site — Tucson

Massachusetts

  • Pfizer Investigational Site — Boston

Trial Details

FieldValue
Enrollment Target 174 participants
Start Date 2004-02
Est. Completion 2008-11
Phase Phase 1

Sponsor

Pfizer

769 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00076024

The ClinicalTrials.gov registry entry for NCT00076024 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 174 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 769 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Breast Neoplasms appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00076024 reports 20 study locations spanning 5 distinct geographic areas — top geographies include Florida, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00076024 about?

NCT00076024 is a clinical study titled "AG-013736 In Combination With Docetaxel Versus Docetaxel Alone For Patients With Metastatic Breast Cancer". The primary purpose of the study is to determine the time to progression of the combination of study drug (AG-013736) and docetaxel versus docetaxel alone in patients who have not received prior chemotherapy for metastatic breast cancer. The secondary purpose of the study is to determine the dose of...

What is the current status of trial NCT00076024?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 174 participants. The study started on 2004-02. Estimated completion is 2008-11.

What conditions does trial NCT00076024 study?

This clinical trial studies the following conditions: Breast Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00076024?

The interventions under investigation include: Placebo (DRUG), Docetaxel (DRUG), AG-013736 (axitinib) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00076024?

This trial is sponsored by Pfizer, which has 769 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00076024 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial