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ClinicalTrials.gov 423 recruiting now early-phase tilt #1 of 28,963 conditions

Breast Cancer: early-phase trial registry

423 of 1,251 indexed Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1 of 28,963 conditions by registered trial count.

1,251 US clinical trials · 423 currently recruiting · #1 of 28,963 conditions by registered trial count

Breast Cancer: 1,251 US clinical trials tracked, 423 recruiting.

Breast Cancer is the subject of 1,251 registered US clinical trials on ClinicalTrials.gov, 423 of them currently open to new participants. 120 are in Phase 3-4 (later-stage) and 491 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 98 of these trials.

Open enrollment, early-phase tilt

Breast Cancer has 1,251 registered US clinical trials, 423 of them open to new participants right now, about 34% of the total.

423
recruiting participants now
34%
of trials open to enrollment
120
in Phase 3-4 (later-stage)
98
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #1 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Breast Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Breast Cancer is recruiting below its size-band peers.

    423 of 1,251 indexed trials (33.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Breast Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 98 of 1,251 trials (7.8%). 367 distinct sponsors appear on at least one study for this condition label.

  3. Typical Breast Cancer enrolment sits around 90 participants.

    Median target enrolment is 90 among the 1,225 trials that report a genuine target (sentinel values excluded). 630 of those (51.4%) plan for fewer than 100 participants.

  4. Breast Cancer research is mostly interventional.

    1,015 interventional and 236 observational studies make up this index (81.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1235Phase 2256Phase 3100Phase 420

Open and recent trials

1,251 total, page 22 of 26

COMPLETED NA 40 participants

Narrative Visualization for Breast Cancer Survivors' Physical Activity

The University of Texas Medical Branch, Galveston

NCT03612596

COMPLETED NA 40 participants

Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial

University of Illinois at Urbana-Champaign

NCT03702712

COMPLETED 40 participants

Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis

Mayo Clinic

NCT03519438

COMPLETED Early Phase 1 39 participants

S-equol in Women With Triple Negative Breast Cancer

The University of Texas Health Science Center at San Antonio

NCT02352025

COMPLETED NA 39 participants

Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer

University of Miami

NCT00450723

COMPLETED NA 39 participants

Effect of Increased Light Exposure on Fatigue in Breast Cancer

University of California, San Diego

NCT00478257

COMPLETED 39 participants

Patient-centered Communication About Healthy Weight in Early Breast Cancer

UNC Lineberger Comprehensive Cancer Center

NCT04504201

COMPLETED NA 39 participants

Yoga Practice for Breast or Ovarian Cancer Patients

Memorial Sloan Kettering Cancer Center

NCT02305498

COMPLETED 39 participants

Pilot Functional Imaging Study to Evaluate Mechanisms Underlying Chronic Pain in Breast Cancer Patients

Lynn Henry

NCT01639417

COMPLETED NA 38 participants

Paclitaxel and Radiation Therapy in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer

Vanderbilt-Ingram Cancer Center

NCT00647218

COMPLETED NA 38 participants

Effect of Sukshma Vyayama Yoga on Aromatase Inhibitor-Induced Arthralgia in Breast Cancer Survivors

AshtaYoga

NCT04042870

COMPLETED 37 participants

Bone Response in Metastatic Breast Cancer Involving Bones

M.D. Anderson Cancer Center

NCT00420433

COMPLETED Phase 2 37 participants

Docetaxel Plus Imatinib Mesylate in Metastatic Breast Cancer

SCRI Development Innovations

NCT00193180

COMPLETED NA 36 participants

Patient-Assisted Compression in 3D - Impact on Image Quality and Workflow

GE Healthcare

NCT03456427

COMPLETED Phase 2 36 participants

Exemestane in Treating Postmenopausal Women With Stage IV Breast Cancer

City of Hope Medical Center

NCT00810797

COMPLETED NA 35 participants

Culturally Aware AET Non-Initiation Intervention

Massachusetts General Hospital

NCT05465408

COMPLETED NA 35 participants

Effects of Meditation on Cognitive Function and Quality of Life

M.D. Anderson Cancer Center

NCT02162329

COMPLETED NA 34 participants

Pre-Surgery Positron Emission Mammography in Patients With Newly Diagnosed Breast Cancer

Swedish Medical Center

NCT01241721

COMPLETED Phase 2 34 participants

Campath-1H + FK506 and Methylprednisolone for GVHD

Case Comprehensive Cancer Center

NCT00109993

COMPLETED NA 33 participants

Reducing Distress and Depressive-symptoms in Rural Women

University of Nebraska

NCT03465813

COMPLETED Phase 2 33 participants

Health SMART (Stress Management and Relaxation Training)

Fred Hutchinson Cancer Center

NCT01048528

COMPLETED Phase 1 32 participants

A Study Of Changes In PD-L1 Expression During Preoperative Treatment With Nab-Paclitaxel And Pembrolizumab In Hormone Receptor-Positive Breast Cancer

Adrienne G. Waks

NCT02999477

COMPLETED NA 32 participants

Preoperative Accelerated Partial Breast Irradiation (APBI) for Women With Stage I and Select IIA Breast Cancer

University of Maryland, Baltimore

NCT01014715

COMPLETED NA 32 participants

Healing Touch During Chemotherapy Infusions for Women With Breast Cancer

Stanford University

NCT00533663

COMPLETED Phase 2 31 participants

Irinotecan and Etoposide in Treating Patients With Recurrent, Locally Advanced, or Metastatic Breast Cancer

University of Arizona

NCT00693719

COMPLETED NA 31 participants

Study on Physical Activity's Relationship With Cancer and Cognition

University of Nebraska

NCT03980626

COMPLETED NA 31 participants

Activity & Cognition After Treatment for Breast Cancer

University of Illinois at Urbana-Champaign

NCT02592070

COMPLETED Phase 1 31 participants

Gefitinib, Trastuzumab, and Docetaxel in Treating Patients With Metastatic Breast Cancer

City of Hope Medical Center

NCT00086957

COMPLETED 30 participants

Preserving Function in Breast Cancer Patients

Dartmouth-Hitchcock Medical Center

NCT00429286

COMPLETED Phase 1 30 participants

Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women

UNC Lineberger Comprehensive Cancer Center

NCT00099008

COMPLETED NA 30 participants

Acupuncture in the Management of Post Operative Symptoms in Breast Cancer Patients

Legacy Health System

NCT00419822

COMPLETED NA 30 participants

Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness

Massachusetts General Hospital

NCT02594696

COMPLETED Phase 2 30 participants

A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer

OncoNano Medicine

NCT03735680

COMPLETED NA 30 participants

Mindful Movement in Women Receiving Adjuvant or Neoadjuvant Therapy for Breast Cancer

Washington University School of Medicine

NCT03262831

COMPLETED Phase 1 30 participants

Peripheral Stem Cell Transplantation With or Without Stromagen Following Chemotherapy in Treating Women With Metastatic Breast Cancer

Roswell Park Cancer Institute

NCT00003877

COMPLETED NA 30 participants

Mindfulness for Breast Cancer

NYU Langone Health

NCT02647216

COMPLETED NA 30 participants

Young, Empowered & Strong (YES): The Young Women's Breast Cancer Study 2- Focus on Intervention Pilot

Dana-Farber Cancer Institute

NCT03913936

COMPLETED 30 participants

Study of Ductal Lavage in Women at High Risk for Breast Cancer

University of California, San Francisco

NCT00429988

COMPLETED 30 participants

Emotion Regulation and Cancer Caregiving

Stanford University

NCT06123416

COMPLETED Phase 4 30 participants

Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients

Cancer Center of Irvine

NCT00882596

COMPLETED Phase 1 30 participants

Vinorelbine and XR9576 to Treat Cancer

National Cancer Institute (NCI)

NCT00001944

COMPLETED NA 30 participants

Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors

University of Michigan Rogel Cancer Center

NCT04827459

COMPLETED Early Phase 1 29 participants

Partial Breast Radiation Therapy in Treating Women Undergoing Breast-Conserving Therapy for Early Stage Breast Cancer

Case Comprehensive Cancer Center

NCT00527293

COMPLETED Phase 1 29 participants

Clinical Trial of the Combination of Intravenous Alvespimycin (KOS-1022), Trastuzumab With or Without Paclitaxel in Patients With Advanced Solid Tumor Malignancies or Her2 Positive Metastatic Breast Cancer Who Have Previously Failed Trastuzumab Therapy

Bristol-Myers Squibb

NCT00803556

COMPLETED NA 29 participants

Tamoxifen in the Prevention of Breast Cancer in Hodgkin's Disease Survivors

Dana-Farber Cancer Institute

NCT00165308

COMPLETED 29 participants

Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy

UNC Lineberger Comprehensive Cancer Center

NCT01789983

COMPLETED NA 29 participants

Time Restricted Eating on Cancer Risk

Medical University of South Carolina

NCT05038137

COMPLETED NA 28 participants

Targeted Pain Coping Skills Training (PCST) for Prevention and Treatment of Persistent Post-Mastectomy Pain

Duke University

NCT02439437

COMPLETED Phase 1 28 participants

Bioequivalency Study of Letrozole 2.5 mg Tablets Under Fed Conditions

Roxane Laboratories

NCT01367626

COMPLETED 28 participants

A Pilot Observational Study to Assess Changes in Biochemical Parameters of Ovarian Reserve With Chemotherapy

Lynn Henry

NCT00644683

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Phase Distribution

PhaseTrial count
Phase 1 235
Phase 2 256
Phase 3 100
Phase 4 20

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Breast Cancer right now

423 recruiting of 1,251 indexed (34% open).

Phase mix: 120 late (III/IV) vs 491 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (98 trials), 9 others listed. 50 shown below, recruiting first. #1 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Breast Cancer?

PlainTrial tracks 1,251 US clinical trials for Breast Cancer, of which 423 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Breast Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.