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ClinicalTrials.gov 70 recruiting now full pipeline #15 of 28,963 conditions

Asthma: full-pipeline trial registry

70 of 378 indexed Asthma trials are currently recruiting.

Corpus placement: #15 of 28,963 conditions by registered trial count.

378 US clinical trials · 70 currently recruiting · #15 of 28,963 conditions by registered trial count

Asthma: 378 US clinical trials tracked, 70 recruiting.

Asthma is the subject of 378 registered US clinical trials on ClinicalTrials.gov, 70 of them currently open to new participants. 89 are in Phase 3-4 (later-stage) and 108 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 24 of these trials.

Open enrollment snapshot

Asthma has 378 registered US clinical trials, 70 of them open to new participants right now, about 19% of the total.

70
recruiting participants now
19%
of trials open to enrollment
89
in Phase 3-4 (later-stage)
24
top sponsor: GlaxoSmithKline

Corpus placement: #15 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Asthma on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Asthma is recruiting below its size-band peers.

    70 of 378 indexed trials (18.5%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Asthma trials is spread across many organizations.

    GlaxoSmithKline accounts for 24 of 378 trials (6.3%). 161 distinct sponsors appear on at least one study for this condition label.

  3. Typical Asthma enrolment sits around 144 participants.

    Median target enrolment is 144 among the 375 trials that report a genuine target (sentinel values excluded). 160 of those (42.7%) plan for fewer than 100 participants.

  4. Asthma research is mostly interventional.

    298 interventional and 80 observational studies make up this index (78.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 127Phase 281Phase 351Phase 438

Open and recent trials

378 total, page 6 of 8

COMPLETED Phase 3 92 participants

Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA)

Milton S. Hershey Medical Center

NCT00318708

COMPLETED 88 participants

Pharmacogenetics of b2-Agonists in Asthma.

Nemours Children's Clinic

NCT00708227

COMPLETED 83 participants

Determine the Prevalence and Severity of Asthma in HIV (Human Immunodeficiency Virus) Infected Patients

Duke University

NCT02405026

COMPLETED NA 81 participants

Electronic Monitoring of Medication Adherence in Moderate to Severe Asthma Patients

Montefiore Medical Center

NCT02913092

COMPLETED NA 81 participants

An Electronic Shared Decision-Making Application to Improve Asthma Outcomes

University of Michigan

NCT04951102

COMPLETED Phase 3 80 participants

Evaluate the Effects on Asthma Control of Rabeprazole Given Twice Daily in Subjects With Asthma.

Associated Scientists to Help Minimize Allergies

NCT00214552

COMPLETED NA 80 participants

Adapting and Expanding the Asthma-Educator App

Montefiore Medical Center

NCT03930381

COMPLETED Phase 2 79 participants

Mobile Technology and Online Tools to Improve Asthma Control in Adolescents

3-C Institute for Social Development

NCT02835300

COMPLETED NA 75 participants

Breathing Exercises for Asthma

University of Michigan

NCT02151422

COMPLETED 75 participants

Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma

Deep Breeze

NCT00542282

COMPLETED NA 75 participants

The Study is Enrolling Kids From 8 to 17 Years Old. The BreathSmart Device Attaches to the Inhaler to Measure Adherence.

Connecticut Children's Medical Center

NCT03734861

COMPLETED NA 74 participants

Monitoring Metered Dose Inhalation (MDI) Volume and Timing With a Respimetrix Device in Obstructive Lung Disease.

Pulmonary Critical Care Associates of Baltimore

NCT05495256

COMPLETED Phase 2 72 participants

A Dose-ranging Study to Evaluate Albuterol and Hydrofluoroalkane in Subjects Ages 12 and Older With Persistent Asthma

Teva Branded Pharmaceutical Products R&D

NCT01058863

COMPLETED 72 participants

Lung Fluid and Peripheral Blood Neutrophil IL-5 Surface Receptor in Children With Asthma

University of Virginia

NCT02866487

COMPLETED Phase 2 72 participants

Dose Ranging Study of the Salmeterol Component of Fluticasone /Salmeterol Spiromax Compared to Fluticasone Spiromax and Advair Diskus in Asthma Subjects

Teva Branded Pharmaceutical Products R&D

NCT01772368

COMPLETED Phase 3 70 participants

Evaluation of Efficacy and Safety of E004 in Children With Asthma

Amphastar Pharmaceuticals

NCT01460511

COMPLETED NA 70 participants

Virtual Teach-to-Goal Education vs. Brief Education for Children

University of Chicago

NCT04373499

COMPLETED Phase 2 70 participants

Dose Ranging Pharmacokinetics and Pharmacodynamics Study With Mepolizumab in Asthma Patients With Elevated Eosinophils

GlaxoSmithKline

NCT01366521

COMPLETED Phase 2 70 participants

Vitamin D for Sickle-cell Respiratory Complications

Gary M Brittenham, MD

NCT01443728

COMPLETED NA 68 participants

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

Fred Wamboldt, MD

NCT02766374

COMPLETED NA 66 participants

Trial of Asthma Self-Management Education in Patients With Depressive Symptoms

Hospital for Special Surgery, New York

NCT01708070

COMPLETED NA 63 participants

Sleep Quality in High School Students With Asthma - II

Columbia University

NCT03329066

COMPLETED Phase 4 61 participants

Effect of Nebulized Budesonide and Oral Corticosteroids on Wheezing Episode Relapse in Children

Deborah Gentile

NCT00189436

COMPLETED 60 participants

Oral Bacteria and Allergic Disease in Children

National Institute of Environmental Health Sciences (NIEHS)

NCT00438646

COMPLETED Phase 1 60 participants

Immune Response to Pneumococcal Polysaccharide Vaccine (23-valent) Predicts Asthma Status and Outcomes in Late Adolescents With Asthma

Rohit Divekar

NCT02719379

COMPLETED 59 participants

Association of Transcutaneous Pulse CO-oximetry With Inflammatory Lung Diseases

Boston Children's Hospital

NCT02831348

COMPLETED Phase 2 58 participants

MagniXene MRI Use in Patients With Asthma and COPD to Assess Regional Lung Function by Delineating Ventilation Defects

Xemed

NCT01833390

COMPLETED NA 56 participants

The Childhood Health and Asthma Management Program

University of Florida

NCT02303561

COMPLETED 55 participants

Progression of Airway Obstruction in Childhood Asthma

National Jewish Health

NCT00873873

COMPLETED NA 54 participants

Treatment of Persistent Wheezing in Infants and Children

National Heart, Lung, and Blood Institute (NHLBI)

NCT00301171

COMPLETED Phase 4 52 participants

Positive Expiratory Pressure for the Treatment of Acute Asthma in Children

University of Colorado, Denver

NCT02494076

COMPLETED NA 51 participants

Residential Ventilation Systems and Filtration for Asthma Control in Adults

Illinois Institute of Technology

NCT06098287

COMPLETED Phase 1 50 participants

Electrophilic Fatty Acid Derivatives in Asthma

Sally E. Wenzel MD

NCT01733485

COMPLETED 50 participants

Study to Evaluate the Impact of FeNO Assessments on Asthma Management Decisions in Subject 7 to 60 Years of Age

Aerocrine AB

NCT01729247

COMPLETED 50 participants

Mechanisms of Allergen Immunotherapy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001910

COMPLETED Phase 4 49 participants

Comparison of Single-Dose Efficacy of an Albuterol Breath-Actuated Inhaler (Albuterol-HFA-BAI) Versus an Albuterol Metered-Dose Inhaler (Albuterol-HFA-MDI) in Participants With Asthma

Teva Branded Pharmaceutical Products R&D

NCT00530062

COMPLETED Phase 2 49 participants

Oxidative Stress in Asthma

Bastiaan Driehuys

NCT04512547

COMPLETED NA 48 participants

Functional Medicine in Asthma (FAst) Study

The Cleveland Clinic

NCT02808689

COMPLETED Phase 2 46 participants

Assessment of the Safety, Efficacy, PK, and Extrapulmonary Pharmacodynamics (PD) of Albuterol Sulfate Pressurized Inhalation Suspension (Hereafter Referred to as AS MDI) Compared to Proventil as an Active Control in Subjects With Asthma

AstraZeneca

NCT03371459

COMPLETED NA 45 participants

Effect of Whole Body Periodic Acceleration on Airway Endothelial Function

University of Miami

NCT01213706

COMPLETED Phase 1 44 participants

Evaluation of Regional Ventilation Using 19F MRI of Inert Perfluorinated Gases Mixed With Oxygen

Hal C Charles

NCT01710449

COMPLETED Phase 4 44 participants

Dose Response Effects of Inhaled Fluticasone on Airway Effects of Hypertonic-saline in Asthma

University of California, San Francisco

NCT00606242

COMPLETED Phase 2 43 participants

Family-Focused, Stress-Reduction Program to Improve the Health Care of Urban Children With Asthma

Emory University

NCT00384813

COMPLETED Phase 1 43 participants

Induced Tolerogenic Dendritic Cells as Modulators of Allergic Asthma

Andrew D. Luster, M.D.,Ph.D.

NCT01711593

COMPLETED 43 participants

Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease

Brigham and Women's Hospital

NCT00595114

COMPLETED Phase 2 42 participants

Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma

Sanofi

NCT02573233

COMPLETED Phase 3 41 participants

Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma

Jason Lang, M.D., M.P.H.

NCT03015610

COMPLETED Phase 4 40 participants

The Effect of Cetirizine on Bronchoconstriction

New York City Health and Hospitals Corporation

NCT03340740

COMPLETED Phase 2 40 participants

Phase II Efficacy Study of Aerosolized Recombinant Human IL-4 Receptor in Asthma

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001909

COMPLETED Phase 2 38 participants

Trial of Roflumilast in Asthma Management (TRIM)

Johns Hopkins University

NCT03532490

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Phase Distribution

PhaseTrial count
Phase 1 27
Phase 2 81
Phase 3 51
Phase 4 38

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Asthma right now

70 recruiting of 378 indexed (19% open).

Phase mix: 89 late (III/IV) vs 108 early (I/II) (balanced across stages).

Top sponsor: GlaxoSmithKline (24 trials), 9 others listed. 50 shown below, recruiting first. #15 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Asthma?

PlainTrial tracks 378 US clinical trials for Asthma, of which 70 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Asthma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.