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NCT01733485 · ClinicalTrials.gov registry record · Phase 1

Electrophilic Fatty Acid Derivatives in Asthma

A Phase 1 study of Asthma and Electrophilic Fatty Acids, sponsored by Sally E. Wenzel MD.

Completed
Registry status
Phase 1
Development phase
50
Enrollment target
1
Study location

NCT01733485 is a Phase 1 study of Asthma and Electrophilic Fatty Acids that has completed, run by Sally E. Wenzel MD. The registered enrollment target is 50 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01733485, a Phase 1 study of Asthma and Electrophilic Fatty Acids, has completed, sponsored by Sally E. Wenzel MD.

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

Asthma is an inflammatory disease, which means it causes swelling in the lungs to cause shortness of breath and/or wheezing. There are several asthma medications that help to reduce this problem. The objective of this research study is to characterize the presence of electrophilic fatty acids in the bronchial airway of subjects with controlled asthma at baseline and after treatment with Aspirin, Indomethacin, or no treatment at all. The presence of electrophilic fatty acids may indicate inflammation. Aspirin and Indomethacin are known to respectively increase and inhibit the formation of electrophilic fatty acids. By gaining a better understanding of how electrophilic fatty acids work and how they respond to different treatment, researchers hope to be able to find better ways to lessen airway inflammation in asthma in the future.

Interventions

  • DRUG Aspirin
  • DRUG Indomethacin

Study Locations (1)

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2011-10
Est. Completion 2017-06
Phase Phase 1

Sponsor

Sally E. Wenzel MD

3 total trials

What the Registry Record Tells You About NCT01733485

The ClinicalTrials.gov registry entry for NCT01733485 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower). The listed sponsor is Sally E. Wenzel MD, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which Aspirin is the first listed.

NCT01733485 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT01733485 about?

NCT01733485 is a clinical study titled "Electrophilic Fatty Acid Derivatives in Asthma". Asthma is an inflammatory disease, which means it causes swelling in the lungs to cause shortness of breath and/or wheezing. There are several asthma medications that help to reduce this problem. The objective of this research study is to characterize the presence of electrophilic fatty acids in th...

What is the current status of trial NCT01733485?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2011-10. Estimated completion is 2017-06.

What conditions does trial NCT01733485 study?

This clinical trial studies the following conditions: Asthma, Electrophilic Fatty Acids.

What interventions are being tested in trial NCT01733485?

The interventions under investigation include: Aspirin (DRUG), Indomethacin (DRUG).

Who is sponsoring clinical trial NCT01733485?

This trial is sponsored by Sally E. Wenzel MD, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01733485 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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