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NCT03015610 · ClinicalTrials.gov registry record · Phase 3

Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma

A Phase 3 study of Asthma and Gastroesophageal Reflux, sponsored by Jason Lang, M.D., M.P.H..

Completed
Registry status
Phase 3
Development phase
41
Enrollment target
2
Study locations

NCT03015610 is a Phase 3 study of Asthma and Gastroesophageal Reflux that has completed, run by Jason Lang, M.D., M.P.H.. The registered enrollment target is 41 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT03015610, a Phase 3 study of Asthma and Gastroesophageal Reflux, has completed, sponsored by Jason Lang, M.D., M.P.H..

COMPLETED
Registry status
Phase 3
Development phase
41 participants
Enrollment target
2
Study locations

Study Summary

This study will evaluate the effect of CYP2C19 and ABCB1 genes on pharmacokinetics of lansoprazole in children with mild gastroesophageal reflux (GER) and uncontrolled asthma. It will determine if genotype-guided lansoprazole dosing of lansoprazole improves GER and asthma control.

Interventions

  • DRUG commercially available lansoprazole
  • DRUG matched placebo

Study Locations (2)

Florida

  • Nemours Children's Specialty Care - Jacksonville

North Carolina

  • Duke University Medical Center - Durham

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2017-10-31
Est. Completion 2024-01-18
Phase Phase 3

Sponsor

Jason Lang, M.D., M.P.H.

1 total trials

What the Registry Record Tells You About NCT03015610

The ClinicalTrials.gov registry entry for NCT03015610 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (97% lower). The listed sponsor is Jason Lang, M.D., M.P.H., which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which commercially available lansoprazole is the first listed.

NCT03015610 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Florida, North Carolina.

Frequently Asked Questions

What is clinical trial NCT03015610 about?

NCT03015610 is a clinical study titled "Genotype-tailored Treatment of Symptomatic Acid-Reflux in Children With Uncontrolled Asthma". This study will evaluate the effect of CYP2C19 and ABCB1 genes on pharmacokinetics of lansoprazole in children with mild gastroesophageal reflux (GER) and uncontrolled asthma. It will determine if genotype-guided lansoprazole dosing of lansoprazole improves GER and asthma control.

What is the current status of trial NCT03015610?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 41 participants. The study started on 2017-10-31. Estimated completion is 2024-01-18.

What conditions does trial NCT03015610 study?

This clinical trial studies the following conditions: Asthma, Gastroesophageal Reflux.

What interventions are being tested in trial NCT03015610?

The interventions under investigation include: commercially available lansoprazole (DRUG), matched placebo (DRUG).

Who is sponsoring clinical trial NCT03015610?

This trial is sponsored by Jason Lang, M.D., M.P.H., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03015610 being conducted?

This trial has 2 study locations across Florida, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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