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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 4 of 8

ACTIVE NOT RECRUITING NA 1,100 participants

Examining Bluetooth Haptic Device Use for Pain and Anxiety Reduction in Vascular Access Procedures

Stanford University

NCT06234228

ACTIVE NOT RECRUITING NA 1,093 participants

EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain

AppliedVR

NCT05263037

ACTIVE NOT RECRUITING NA 805 participants

More Individualized Care: Assessment and Recovery Through Engagement

Kaiser Permanente

NCT05122676

ACTIVE NOT RECRUITING NA 456 participants

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

University of Michigan

NCT05451589

ACTIVE NOT RECRUITING NA 412 participants

Supporting Family Caregivers of Persons With Dementia

University of Pennsylvania

NCT05336344

ACTIVE NOT RECRUITING NA 405 participants

Well-being in Students and Teachers Study

University of Illinois at Chicago

NCT06203288

ACTIVE NOT RECRUITING NA 308 participants

Resettled Refugee Families for Healing

Washington University School of Medicine

NCT06176638

ACTIVE NOT RECRUITING NA 300 participants

Scientific Information and Beliefs About Psychological Therapy

University of California, Irvine

NCT06825000

ACTIVE NOT RECRUITING NA 240 participants

Preventing Anxiety and Depression in Older Hispanics

University of Miami

NCT03870360

ACTIVE NOT RECRUITING Phase 2 240 participants

Improving Mental Health Among the LGBTQ+ Community

Brown University

NCT05540067

ACTIVE NOT RECRUITING NA 225 participants

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

VA Office of Research and Development

NCT04523779

ACTIVE NOT RECRUITING Phase 4 150 participants

Brain Stimulation & Generalized Anxiety Study

ProofPilot

NCT04751864

ACTIVE NOT RECRUITING NA 150 participants

Stress Reduction After Use of a Haptic Vibrotactile Trigger Technology Patch: Analysis and Assessment

SuperPatch Limited

NCT06708715

ACTIVE NOT RECRUITING NA 150 participants

Intervention Trial for Healthcare Workers With Anxiety

University of California, Los Angeles

NCT06460285

ACTIVE NOT RECRUITING NA 150 participants

You & Me Healthy: Youth Empowered Self-Care Substudy (YES)

Duke University

NCT06255093

ACTIVE NOT RECRUITING NA 150 participants

Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions

Viome

NCT05563857

ACTIVE NOT RECRUITING NA 144 participants

Factorial Optimization Trial to Test Effects of Coping Intervention Components

Arizona State University

NCT05822687

ACTIVE NOT RECRUITING NA 141 participants

The Group Risk Reduction Intervention Therapy (GRRIT) Project

University of North Carolina, Charlotte

NCT05401838

ACTIVE NOT RECRUITING 122 participants

Probiotics for Anxiety Study

Verb Biotics

NCT06466603

ACTIVE NOT RECRUITING NA 120 participants

Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients

University of California, Irvine

NCT05979103

ACTIVE NOT RECRUITING NA 117 participants

This Study Explores the Mental Health Impact of Two Akashic Records Sessions.

Rasa Healing

NCT07219914

ACTIVE NOT RECRUITING NA 111 participants

Essential Oils for Electrocautery

Northwestern University

NCT04260867

ACTIVE NOT RECRUITING NA 111 participants

Exercise for Anxiety

NYU Langone Health

NCT04638946

ACTIVE NOT RECRUITING NA 100 participants

Smartphones Aggravating Anxiety Symptoms

Mayo Clinic

NCT06361342

ACTIVE NOT RECRUITING Phase 2 100 participants

Evaluating Buspirone to Treat Opioid Withdrawal

Johns Hopkins University

NCT05511909

ACTIVE NOT RECRUITING NA 90 participants

Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults

Northwestern University

NCT05325944

ACTIVE NOT RECRUITING NA 90 participants

Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers

Thomas Jefferson University

NCT05132881

ACTIVE NOT RECRUITING NA 73 participants

Facing Your Fears: Adolescents With ASD and Intellectual Disability

University of Colorado, Denver

NCT05131425

ACTIVE NOT RECRUITING NA 70 participants

Brief, High-dose rTMS for Depression

Medical University of South Carolina

NCT04657432

ACTIVE NOT RECRUITING Phase 2 60 participants

RCT of CBD for Anxiety in Advanced Breast Cancer

Dana-Farber Cancer Institute

NCT04482244

ACTIVE NOT RECRUITING NA 50 participants

Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors

University of Michigan Rogel Cancer Center

NCT05911269

ACTIVE NOT RECRUITING NA 44 participants

LIFU for Anxiety Management

Virginia Polytechnic Institute and State University

NCT05839847

ACTIVE NOT RECRUITING NA 35 participants

Using CalmiGo to Manage Anxiety and Panic Attack Symptoms in the Emergency Department

Yves Duroseau

NCT03884712

ACTIVE NOT RECRUITING NA 35 participants

Meditation Therapy in Improving Anxiety and Depression in Cancer Patients With Psychosocial Distress

M.D. Anderson Cancer Center

NCT02988271

ACTIVE NOT RECRUITING NA 30 participants

Evaluation of the Effects of Human-Animal Interaction on Anxiety in Graduate Students

Wichita State University

NCT07036354

ACTIVE NOT RECRUITING NA 24 participants

An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy

Teachers College, Columbia University

NCT05590741

ACTIVE NOT RECRUITING NA 21 participants

The Counselor Led Resident Wellness Study

University of Nevada, Reno

NCT07053111

ACTIVE NOT RECRUITING Phase 1 17 participants

Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders

University of Minnesota

NCT06545071

ACTIVE NOT RECRUITING NA 15 participants

PRISM for Depression and Anxiety in Young Adults With Cancer

Dana-Farber Cancer Institute

NCT06502483

ACTIVE NOT RECRUITING NA 14 participants

Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders

University of Arizona

NCT03540745

ACTIVE NOT RECRUITING NA 8 participants

Rare Group Problem Management Plus

Children's National Research Institute

NCT06548022

COMPLETED NA 10,821 participants

Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care

University of California, San Francisco

NCT03217058

COMPLETED 6,894 participants

Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic

Pregistry

NCT04385238

COMPLETED NA 6,500 participants

Mental Health Pathways in Internet Support Groups

Carnegie Mellon University

NCT02396472

COMPLETED NA 4,370 participants

SSIs for Mental Health and Loneliness

University of California, Irvine

NCT05687162

COMPLETED 4,193 participants

National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01591694

COMPLETED NA 2,118 participants

Providing Mental Health Precision Treatment

University of Michigan

NCT04342494

COMPLETED Phase 2 1,748 participants

Interpretation Training to Reduce Anxiety: Evaluating Technology-based Delivery Models and Methods to Reduce Attrition

University of Virginia

NCT03498651

COMPLETED NA 1,362 participants

Thriving Together: Supporting Resilience in the Healthcare Workforce

Johns Hopkins University

NCT05321381

COMPLETED NA 838 participants

Mobile Mental Health Apps for Suicide Prevention

University of Washington

NCT04536935

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.