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ClinicalTrials.gov 148 recruiting now official registry

Anxiety clinical trials

148 of 367 indexed Anxiety trials are currently recruiting.

367 US clinical trials · 148 currently recruiting

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

The research picture

Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.

148
recruiting participants now
40%
of trials open to enrollment
15
in Phase 3–4 (later-stage)
11
top sponsor: University of California, Los Angeles
Phase 113Phase 225Phase 36Phase 49

Active & Recent Trials

367 total, page 4 of 8

ACTIVE NOT RECRUITING NA 1,100 participants

Examining Bluetooth Haptic Device Use for Pain and Anxiety Reduction in Vascular Access Procedures

Stanford University

NCT06234228

ACTIVE NOT RECRUITING NA 1,093 participants

EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain

AppliedVR

NCT05263037

ACTIVE NOT RECRUITING NA 805 participants

More Individualized Care: Assessment and Recovery Through Engagement

Kaiser Permanente

NCT05122676

ACTIVE NOT RECRUITING NA 456 participants

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

University of Michigan

NCT05451589

ACTIVE NOT RECRUITING NA 412 participants

Supporting Family Caregivers of Persons With Dementia

University of Pennsylvania

NCT05336344

ACTIVE NOT RECRUITING NA 405 participants

Well-being in Students and Teachers Study

University of Illinois at Chicago

NCT06203288

ACTIVE NOT RECRUITING NA 308 participants

Resettled Refugee Families for Healing

Washington University School of Medicine

NCT06176638

ACTIVE NOT RECRUITING NA 300 participants

Scientific Information and Beliefs About Psychological Therapy

University of California, Irvine

NCT06825000

ACTIVE NOT RECRUITING NA 240 participants

Preventing Anxiety and Depression in Older Hispanics

University of Miami

NCT03870360

ACTIVE NOT RECRUITING Phase 2 240 participants

Improving Mental Health Among the LGBTQ+ Community

Brown University

NCT05540067

ACTIVE NOT RECRUITING NA 225 participants

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

VA Office of Research and Development

NCT04523779

ACTIVE NOT RECRUITING Phase 4 150 participants

Brain Stimulation & Generalized Anxiety Study

ProofPilot

NCT04751864

ACTIVE NOT RECRUITING NA 150 participants

Stress Reduction After Use of a Haptic Vibrotactile Trigger Technology Patch: Analysis and Assessment

SuperPatch Limited

NCT06708715

ACTIVE NOT RECRUITING NA 150 participants

Intervention Trial for Healthcare Workers With Anxiety

University of California, Los Angeles

NCT06460285

ACTIVE NOT RECRUITING NA 150 participants

You & Me Healthy: Youth Empowered Self-Care Substudy (YES)

Duke University

NCT06255093

ACTIVE NOT RECRUITING NA 150 participants

Viome Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions

Viome

NCT05563857

ACTIVE NOT RECRUITING NA 144 participants

Factorial Optimization Trial to Test Effects of Coping Intervention Components

Arizona State University

NCT05822687

ACTIVE NOT RECRUITING NA 141 participants

The Group Risk Reduction Intervention Therapy (GRRIT) Project

University of North Carolina, Charlotte

NCT05401838

ACTIVE NOT RECRUITING 122 participants

Probiotics for Anxiety Study

Verb Biotics

NCT06466603

ACTIVE NOT RECRUITING NA 120 participants

Music Genre Stereotypes to Boost Relaxation in Chronic Pain Patients

University of California, Irvine

NCT05979103

ACTIVE NOT RECRUITING NA 117 participants

This Study Explores the Mental Health Impact of Two Akashic Records Sessions.

Rasa Healing

NCT07219914

ACTIVE NOT RECRUITING NA 111 participants

Essential Oils for Electrocautery

Northwestern University

NCT04260867

ACTIVE NOT RECRUITING NA 111 participants

Exercise for Anxiety

NYU Langone Health

NCT04638946

ACTIVE NOT RECRUITING NA 100 participants

Smartphones Aggravating Anxiety Symptoms

Mayo Clinic

NCT06361342

ACTIVE NOT RECRUITING Phase 2 100 participants

Evaluating Buspirone to Treat Opioid Withdrawal

Johns Hopkins University

NCT05511909

ACTIVE NOT RECRUITING NA 90 participants

Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults

Northwestern University

NCT05325944

ACTIVE NOT RECRUITING NA 90 participants

Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers

Thomas Jefferson University

NCT05132881

ACTIVE NOT RECRUITING NA 73 participants

Facing Your Fears: Adolescents With ASD and Intellectual Disability

University of Colorado, Denver

NCT05131425

ACTIVE NOT RECRUITING NA 70 participants

Brief, High-dose rTMS for Depression

Medical University of South Carolina

NCT04657432

ACTIVE NOT RECRUITING Phase 2 60 participants

RCT of CBD for Anxiety in Advanced Breast Cancer

Dana-Farber Cancer Institute

NCT04482244

ACTIVE NOT RECRUITING NA 50 participants

Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors

University of Michigan Rogel Cancer Center

NCT05911269

ACTIVE NOT RECRUITING NA 44 participants

LIFU for Anxiety Management

Virginia Polytechnic Institute and State University

NCT05839847

ACTIVE NOT RECRUITING NA 35 participants

Using CalmiGo to Manage Anxiety and Panic Attack Symptoms in the Emergency Department

Yves Duroseau

NCT03884712

ACTIVE NOT RECRUITING NA 35 participants

Meditation Therapy in Improving Anxiety and Depression in Cancer Patients With Psychosocial Distress

M.D. Anderson Cancer Center

NCT02988271

ACTIVE NOT RECRUITING NA 30 participants

Evaluation of the Effects of Human-Animal Interaction on Anxiety in Graduate Students

Wichita State University

NCT07036354

ACTIVE NOT RECRUITING NA 24 participants

An Idiographic Examination of Treatment Mechanisms in Emotion Regulation Therapy

Teachers College, Columbia University

NCT05590741

ACTIVE NOT RECRUITING NA 21 participants

The Counselor Led Resident Wellness Study

University of Nevada, Reno

NCT07053111

ACTIVE NOT RECRUITING Phase 1 17 participants

Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders

University of Minnesota

NCT06545071

ACTIVE NOT RECRUITING NA 15 participants

PRISM for Depression and Anxiety in Young Adults With Cancer

Dana-Farber Cancer Institute

NCT06502483

ACTIVE NOT RECRUITING NA 14 participants

Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders

University of Arizona

NCT03540745

ACTIVE NOT RECRUITING NA 8 participants

Rare Group Problem Management Plus

Children's National Research Institute

NCT06548022

COMPLETED NA 10,821 participants

Computerized Substance Use and Depression Screening and Behavioral Treatment in HIV Primary Care

University of California, San Francisco

NCT03217058

COMPLETED 6,894 participants

Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic

Pregistry

NCT04385238

COMPLETED NA 6,500 participants

Mental Health Pathways in Internet Support Groups

Carnegie Mellon University

NCT02396472

COMPLETED NA 4,370 participants

SSIs for Mental Health and Loneliness

University of California, Irvine

NCT05687162

COMPLETED 4,193 participants

National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01591694

COMPLETED NA 2,118 participants

Providing Mental Health Precision Treatment

University of Michigan

NCT04342494

COMPLETED Phase 2 1,748 participants

Interpretation Training to Reduce Anxiety: Evaluating Technology-based Delivery Models and Methods to Reduce Attrition

University of Virginia

NCT03498651

COMPLETED NA 1,362 participants

Thriving Together: Supporting Resilience in the Healthcare Workforce

Johns Hopkins University

NCT05321381

COMPLETED NA 838 participants

Mobile Mental Health Apps for Suicide Prevention

University of Washington

NCT04536935

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anxiety Trial Landscape

367 indexed Anxiety studies · 148 recruiting (40%).

Phase mix: 15 late (III/IV) vs 38 early (I/II).

Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anxiety?

PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anxiety?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.