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NCT04638946 · ClinicalTrials.gov registry record · NA
Exercise for Anxiety
A NA study of Anxiety, sponsored by NYU Langone Health.
- Active
- Registry status
- NA
- Development phase
- 111
- Enrollment target
- 1
- Study location
NCT04638946: Active NA study of Anxiety, sponsored by NYU Langone Health.
NCT04638946 is a NA study of Anxiety that is active but no longer recruiting, run by NYU Langone Health. The registered enrollment target is 111 participants, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04638946, a NA study of Anxiety, is active but no longer recruiting, sponsored by NYU Langone Health.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 111 participants
- Enrollment target
- 1
- Study location
Study Summary
90 sedentary adults with a primary anxiety disorder and high anxiety sensitivity will be randomized to either 8 weeks of 1) low intensity exercise, or 2) flexible titration to high intensity exercise (HIE). Blinded, validated clinician-rated and patient-rated outcomes will be assessed over treatment and at 1- and 3-month follow-up. To better understand what mechanisms influence decisions to exercise in the real-world, we will use of heart rate (HR) as an objective mechanistic target for exercise intensity, examine changes in valuation of exercise through a neuroeconomics task, examine changes in interoceptive sensitivity with a heartbeat detection task, and integrate of ecological momentary assessment (EMA) to measure effects of immediate changes in mood with exercise on anxiety outcomes and adherence.
Primary Outcome
The ASI-3 is an 18-item measure of fear of anxiety sensations with three subscales (physical, cognitive, social concerns). The total score ranges from 0 (lowest anxiety sensitivity) to 72 (highest anxiety sensitivity).
Conditions Studied
Interventions
- BEHAVIORAL Titration to high intensity exercise (T-HIE)
- BEHAVIORAL Low intensity exercise prescription
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 111 participants |
| Start Date | 2021-06-30 |
| Est. Completion | 2026-04-30 |
| Phase | NA |
What the registry record for NCT04638946 still lists
NCT04638946 is an interventional study that assigns participants to a tested intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Anxiety appearing as the primary indexed condition, and to 2 interventions - of which Titration to high intensity exercise (T-HIE) is the first listed.
NCT04638946 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04638946 about?
NCT04638946 is a clinical study titled "Exercise for Anxiety". 90 sedentary adults with a primary anxiety disorder and high anxiety sensitivity will be randomized to either 8 weeks of 1) low intensity exercise, or 2) flexible titration to high intensity exercise (HIE). Blinded, validated clinician-rated and patient-rated outcomes will be assessed over treatment...
What is the current status of trial NCT04638946?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 111 participants. The study started on 2021-06-30. Estimated completion is 2026-04-30.
What conditions does trial NCT04638946 study?
This clinical trial studies the following conditions: Anxiety.
What interventions are being tested in trial NCT04638946?
The interventions under investigation include: Titration to high intensity exercise (T-HIE) (BEHAVIORAL), Low intensity exercise prescription (BEHAVIORAL).
Who is sponsoring clinical trial NCT04638946?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04638946 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anxiety
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04638946's enrollment target sits among peer trials
111 149th of 364 higher than 214 of 364 other Anxiety trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anxiety trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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