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ClinicalTrials.gov 148 recruiting now official registry

Anxiety clinical trials

148 of 367 indexed Anxiety trials are currently recruiting.

367 US clinical trials · 148 currently recruiting

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

The research picture

Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.

148
recruiting participants now
40%
of trials open to enrollment
15
in Phase 3–4 (later-stage)
11
top sponsor: University of California, Los Angeles
Phase 113Phase 225Phase 36Phase 49

Active & Recent Trials

367 total, page 5 of 8

COMPLETED NA 650 participants

The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery

Montefiore Medical Center

NCT06356324

COMPLETED NA 600 participants

Attention Training to Modify Error-related Negativity and Risk for Anxiety in Adolescence

Florida State University

NCT03176004

COMPLETED NA 579 participants

Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety

AltheaDx

NCT02878928

COMPLETED NA 532 participants

Healthy Minds Comparison Study

University of Wisconsin, Madison

NCT06282523

COMPLETED NA 522 participants

Project SOLVE: Trial of a Brief Digital Problem-solving Intervention

Harvard University

NCT04806321

COMPLETED NA 500 participants

Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic

Stony Brook University

NCT04459455

COMPLETED NA 500 participants

Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes

Radicle Science

NCT06749288

COMPLETED NA 500 participants

Self-Management Program for Persons With Limb Loss

Johns Hopkins Bloomberg School of Public Health

NCT00198692

COMPLETED NA 500 participants

Tranquil Moments II-CBT vs. Yoga for Worry

Wake Forest University Health Sciences

NCT02968238

COMPLETED Phase 2 487 participants

Preventing Persistent Post-Surgical Pain and Dysfunction

Barbara A Rakel

NCT03965897

COMPLETED NA 485 participants

Treatment of Parental Anxiety Virtual Reality (VR)

Stanford University

NCT05729347

COMPLETED 483 participants

Moral Injury Symptom Scale/Moral Injury Outcome Scale

AdventHealth

NCT04261751

COMPLETED NA 415 participants

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

Medical University of South Carolina

NCT04630249

COMPLETED Phase 2 364 participants

Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation

University of Minnesota

NCT00440700

COMPLETED NA 340 participants

Use of Death Cafes to Prevent Burnout in ICU Healthcare Employees

Tulane University School of Medicine

NCT04347811

COMPLETED NA 324 participants

Daily Assessment of Mood and Social Media Behaviors Study

Southern Methodist University

NCT04349423

COMPLETED NA 321 participants

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

The Cleveland Clinic

NCT05374096

COMPLETED NA 299 participants

Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women

Ohio State University

NCT03416010

COMPLETED NA 296 participants

Comprehensive vs. Assisted Management of Mood and Pain Symptoms

VA Office of Research and Development

NCT01757301

COMPLETED Phase 2 275 participants

Low-intensity Stepped Care for Internalizing Distress

Indiana University

NCT05441111

COMPLETED Phase 2 268 participants

Personal Relevance of Psychotherapy for Asian Americans

IRIS Media

NCT06632158

COMPLETED NA 260 participants

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

Cambridge Health Alliance

NCT04278586

COMPLETED NA 232 participants

Family-centered Mental Health Promotion Intervention

University of Massachusetts, Amherst

NCT04453709

COMPLETED NA 226 participants

Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women

University of Washington

NCT03545282

COMPLETED NA 220 participants

Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders

AltheaDx

NCT02411123

COMPLETED NA 211 participants

Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder

Veterans Medical Research Foundation

NCT01158001

COMPLETED NA 210 participants

Chatbot for Depression, Anxiety, and Eating Disorders

Dartmouth-Hitchcock Medical Center

NCT06013137

COMPLETED NA 203 participants

The Clinic Treatment Project

Judge Baker Children's Center

NCT01178554

COMPLETED NA 201 participants

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

Medical College of Wisconsin

NCT03980067

COMPLETED 186 participants

Living With Sickle Cell Disease in the COVID-19 Pandemic

National Human Genome Research Institute (NHGRI)

NCT04417673

COMPLETED NA 185 participants

Brief Cognitive Behavioral Therapy (CBT) for Pediatric Anxiety and Depression in Primary Care

San Diego State University

NCT01147614

COMPLETED NA 178 participants

Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety

Yale University

NCT06111742

COMPLETED NA 177 participants

Brief Anxiety Skills Training Intervention for Veterans in Primary Care

VA Office of Research and Development

NCT04829240

COMPLETED 168 participants

Exploring Virtual Reality in Clinical Care - Impacts on Patient Distress, Parental Anxiety and Nurse Satisfaction

Virginia Commonwealth University

NCT07280910

COMPLETED 163 participants

Stress and Coping in Caregivers of Younger Patients With Cancer

Wake Forest University Health Sciences

NCT02725385

COMPLETED Phase 2 161 participants

An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress

Janssen Research & Development

NCT02498392

COMPLETED NA 160 participants

Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans

Veterans Medical Research Foundation

NCT01253044

COMPLETED NA 153 participants

Collaborative Care for Women Veterans

VA Office of Research and Development

NCT02950961

COMPLETED Phase 3 150 participants

Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth

Wayne State University

NCT01594606

COMPLETED NA 150 participants

Participatory Messaging in the UCLA Psychiatry Partial Hospitalization and Intensive Outpatient Programs

University of California, Los Angeles

NCT02708940

COMPLETED 150 participants

Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

Ran Anbar

NCT02158338

COMPLETED NA 146 participants

Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.

Actualize Therapy

NCT03500536

COMPLETED NA 144 participants

Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy

Foundation for Orthopaedic Research and Education

NCT04889833

COMPLETED NA 140 participants

Efficacy of the Tony Robbins Rapid Planning Method (RPM)

Applied Science & Performance Institute

NCT06539949

COMPLETED NA 139 participants

Effect of Intra-procedure Music on Anxiety

NYU Langone Health

NCT03665662

COMPLETED Phase 4 135 participants

Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

Indiana University

NCT02213900

COMPLETED NA 134 participants

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

Stanford University

NCT06001697

COMPLETED NA 128 participants

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

Duke University

NCT02516332

COMPLETED 124 participants

A Mind-Body Medicine Curriculum for Peer Counselors

The Center for Mind-Body Medicine

NCT03718845

COMPLETED Phase 3 120 participants

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

University Hospitals Cleveland Medical Center

NCT00671853

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anxiety Trial Landscape

367 indexed Anxiety studies · 148 recruiting (40%).

Phase mix: 15 late (III/IV) vs 38 early (I/II).

Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anxiety?

PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anxiety?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.