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Anxiety clinical trials
148 of 367 indexed Anxiety trials are currently recruiting.
367 US clinical trials · 148 currently recruiting
Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.
The research picture
Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.
- 148
- recruiting participants now
- 40%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 11
- top sponsor: University of California, Los Angeles
Active & Recent Trials
367 total, page 5 of 8
The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery
Montefiore Medical Center
NCT06356324
Attention Training to Modify Error-related Negativity and Risk for Anxiety in Adolescence
Florida State University
NCT03176004
Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety
AltheaDx
NCT02878928
Healthy Minds Comparison Study
University of Wisconsin, Madison
NCT06282523
Project SOLVE: Trial of a Brief Digital Problem-solving Intervention
Harvard University
NCT04806321
Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic
Stony Brook University
NCT04459455
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
Radicle Science
NCT06749288
Self-Management Program for Persons With Limb Loss
Johns Hopkins Bloomberg School of Public Health
NCT00198692
Tranquil Moments II-CBT vs. Yoga for Worry
Wake Forest University Health Sciences
NCT02968238
Preventing Persistent Post-Surgical Pain and Dysfunction
Barbara A Rakel
NCT03965897
Treatment of Parental Anxiety Virtual Reality (VR)
Stanford University
NCT05729347
Moral Injury Symptom Scale/Moral Injury Outcome Scale
AdventHealth
NCT04261751
Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT
Medical University of South Carolina
NCT04630249
Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation
University of Minnesota
NCT00440700
Use of Death Cafes to Prevent Burnout in ICU Healthcare Employees
Tulane University School of Medicine
NCT04347811
Daily Assessment of Mood and Social Media Behaviors Study
Southern Methodist University
NCT04349423
Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery
The Cleveland Clinic
NCT05374096
Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
Ohio State University
NCT03416010
Comprehensive vs. Assisted Management of Mood and Pain Symptoms
VA Office of Research and Development
NCT01757301
Low-intensity Stepped Care for Internalizing Distress
Indiana University
NCT05441111
Personal Relevance of Psychotherapy for Asian Americans
IRIS Media
NCT06632158
Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)
Cambridge Health Alliance
NCT04278586
Family-centered Mental Health Promotion Intervention
University of Massachusetts, Amherst
NCT04453709
Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women
University of Washington
NCT03545282
Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders
AltheaDx
NCT02411123
Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder
Veterans Medical Research Foundation
NCT01158001
Chatbot for Depression, Anxiety, and Eating Disorders
Dartmouth-Hitchcock Medical Center
NCT06013137
The Clinic Treatment Project
Judge Baker Children's Center
NCT01178554
Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department
Medical College of Wisconsin
NCT03980067
Living With Sickle Cell Disease in the COVID-19 Pandemic
National Human Genome Research Institute (NHGRI)
NCT04417673
Brief Cognitive Behavioral Therapy (CBT) for Pediatric Anxiety and Depression in Primary Care
San Diego State University
NCT01147614
Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety
Yale University
NCT06111742
Brief Anxiety Skills Training Intervention for Veterans in Primary Care
VA Office of Research and Development
NCT04829240
Exploring Virtual Reality in Clinical Care - Impacts on Patient Distress, Parental Anxiety and Nurse Satisfaction
Virginia Commonwealth University
NCT07280910
Stress and Coping in Caregivers of Younger Patients With Cancer
Wake Forest University Health Sciences
NCT02725385
An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress
Janssen Research & Development
NCT02498392
Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans
Veterans Medical Research Foundation
NCT01253044
Collaborative Care for Women Veterans
VA Office of Research and Development
NCT02950961
Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth
Wayne State University
NCT01594606
Participatory Messaging in the UCLA Psychiatry Partial Hospitalization and Intensive Outpatient Programs
University of California, Los Angeles
NCT02708940
Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?
Ran Anbar
NCT02158338
Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.
Actualize Therapy
NCT03500536
Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy
Foundation for Orthopaedic Research and Education
NCT04889833
Efficacy of the Tony Robbins Rapid Planning Method (RPM)
Applied Science & Performance Institute
NCT06539949
Effect of Intra-procedure Music on Anxiety
NYU Langone Health
NCT03665662
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Indiana University
NCT02213900
Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness
Stanford University
NCT06001697
Exercise and Pharmacotherapy for Anxiety in Cardiac Patients
Duke University
NCT02516332
A Mind-Body Medicine Curriculum for Peer Counselors
The Center for Mind-Body Medicine
NCT03718845
Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
University Hospitals Cleveland Medical Center
NCT00671853
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 25 |
| Phase 3 | 6 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Trial Landscape
367 indexed Anxiety studies · 148 recruiting (40%).
Phase mix: 15 late (III/IV) vs 38 early (I/II).
Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety?
PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.