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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 5 of 8

COMPLETED NA 650 participants

The Effects of Music and Television on Intraoperative Hypertensive Events in Cataract Surgery

Montefiore Medical Center

NCT06356324

COMPLETED NA 600 participants

Attention Training to Modify Error-related Negativity and Risk for Anxiety in Adolescence

Florida State University

NCT03176004

COMPLETED NA 579 participants

Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety

AltheaDx

NCT02878928

COMPLETED NA 532 participants

Healthy Minds Comparison Study

University of Wisconsin, Madison

NCT06282523

COMPLETED NA 522 participants

Project SOLVE: Trial of a Brief Digital Problem-solving Intervention

Harvard University

NCT04806321

COMPLETED NA 500 participants

Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic

Stony Brook University

NCT04459455

COMPLETED NA 500 participants

Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes

Radicle Science

NCT06749288

COMPLETED NA 500 participants

Self-Management Program for Persons With Limb Loss

Johns Hopkins Bloomberg School of Public Health

NCT00198692

COMPLETED NA 500 participants

Tranquil Moments II-CBT vs. Yoga for Worry

Wake Forest University Health Sciences

NCT02968238

COMPLETED Phase 2 487 participants

Preventing Persistent Post-Surgical Pain and Dysfunction

Barbara A Rakel

NCT03965897

COMPLETED NA 485 participants

Treatment of Parental Anxiety Virtual Reality (VR)

Stanford University

NCT05729347

COMPLETED 483 participants

Moral Injury Symptom Scale/Moral Injury Outcome Scale

AdventHealth

NCT04261751

COMPLETED NA 415 participants

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

Medical University of South Carolina

NCT04630249

COMPLETED Phase 2 364 participants

Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation

University of Minnesota

NCT00440700

COMPLETED NA 340 participants

Use of Death Cafes to Prevent Burnout in ICU Healthcare Employees

Tulane University School of Medicine

NCT04347811

COMPLETED NA 324 participants

Daily Assessment of Mood and Social Media Behaviors Study

Southern Methodist University

NCT04349423

COMPLETED NA 321 participants

Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery

The Cleveland Clinic

NCT05374096

COMPLETED NA 299 participants

Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women

Ohio State University

NCT03416010

COMPLETED NA 296 participants

Comprehensive vs. Assisted Management of Mood and Pain Symptoms

VA Office of Research and Development

NCT01757301

COMPLETED Phase 2 275 participants

Low-intensity Stepped Care for Internalizing Distress

Indiana University

NCT05441111

COMPLETED Phase 2 268 participants

Personal Relevance of Psychotherapy for Asian Americans

IRIS Media

NCT06632158

COMPLETED NA 260 participants

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

Cambridge Health Alliance

NCT04278586

COMPLETED NA 232 participants

Family-centered Mental Health Promotion Intervention

University of Massachusetts, Amherst

NCT04453709

COMPLETED NA 226 participants

Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women

University of Washington

NCT03545282

COMPLETED NA 220 participants

Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders

AltheaDx

NCT02411123

COMPLETED NA 211 participants

Telemedicine for Improved Delivery of Psychosocial Treatments for Post Traumatic Stress Disorder

Veterans Medical Research Foundation

NCT01158001

COMPLETED NA 210 participants

Chatbot for Depression, Anxiety, and Eating Disorders

Dartmouth-Hitchcock Medical Center

NCT06013137

COMPLETED NA 203 participants

The Clinic Treatment Project

Judge Baker Children's Center

NCT01178554

COMPLETED NA 201 participants

Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department

Medical College of Wisconsin

NCT03980067

COMPLETED 186 participants

Living With Sickle Cell Disease in the COVID-19 Pandemic

National Human Genome Research Institute (NHGRI)

NCT04417673

COMPLETED NA 185 participants

Brief Cognitive Behavioral Therapy (CBT) for Pediatric Anxiety and Depression in Primary Care

San Diego State University

NCT01147614

COMPLETED NA 178 participants

Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety

Yale University

NCT06111742

COMPLETED NA 177 participants

Brief Anxiety Skills Training Intervention for Veterans in Primary Care

VA Office of Research and Development

NCT04829240

COMPLETED 168 participants

Exploring Virtual Reality in Clinical Care - Impacts on Patient Distress, Parental Anxiety and Nurse Satisfaction

Virginia Commonwealth University

NCT07280910

COMPLETED 163 participants

Stress and Coping in Caregivers of Younger Patients With Cancer

Wake Forest University Health Sciences

NCT02725385

COMPLETED Phase 2 161 participants

An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress

Janssen Research & Development

NCT02498392

COMPLETED NA 160 participants

Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans

Veterans Medical Research Foundation

NCT01253044

COMPLETED NA 153 participants

Collaborative Care for Women Veterans

VA Office of Research and Development

NCT02950961

COMPLETED Phase 3 150 participants

Randomized Control Trial of an Animal-Assisted Intervention With Adjudicated Youth

Wayne State University

NCT01594606

COMPLETED NA 150 participants

Participatory Messaging in the UCLA Psychiatry Partial Hospitalization and Intensive Outpatient Programs

University of California, Los Angeles

NCT02708940

COMPLETED 150 participants

Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

Ran Anbar

NCT02158338

COMPLETED NA 146 participants

Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.

Actualize Therapy

NCT03500536

COMPLETED NA 144 participants

Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy

Foundation for Orthopaedic Research and Education

NCT04889833

COMPLETED NA 140 participants

Efficacy of the Tony Robbins Rapid Planning Method (RPM)

Applied Science & Performance Institute

NCT06539949

COMPLETED NA 139 participants

Effect of Intra-procedure Music on Anxiety

NYU Langone Health

NCT03665662

COMPLETED Phase 4 135 participants

Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

Indiana University

NCT02213900

COMPLETED NA 134 participants

Nature and Health: How Does Lifestyle and Environment Affect Health and Wellness

Stanford University

NCT06001697

COMPLETED NA 128 participants

Exercise and Pharmacotherapy for Anxiety in Cardiac Patients

Duke University

NCT02516332

COMPLETED 124 participants

A Mind-Body Medicine Curriculum for Peer Counselors

The Center for Mind-Body Medicine

NCT03718845

COMPLETED Phase 3 120 participants

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

University Hospitals Cleveland Medical Center

NCT00671853

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.