Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Anxiety clinical trials
148 of 367 indexed Anxiety trials are currently recruiting.
367 US clinical trials · 148 currently recruiting
Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.
The research picture
Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.
- 148
- recruiting participants now
- 40%
- of trials open to enrollment
- 15
- in Phase 3–4 (later-stage)
- 11
- top sponsor: University of California, Los Angeles
Active & Recent Trials
367 total, page 3 of 8
Collaborative Care for Anxiety and Depression in Epilepsy
Wake Forest University Health Sciences
NCT05559749
Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
Johns Hopkins University
NCT06341972
Neuromodulation of Brain and Emotional Responses to Psychological Stress
University of Pittsburgh
NCT06603064
Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students
University of Alabama, Tuscaloo
NCT07415460
Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments
University of South Dakota
NCT06789731
Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study
SF Research Institute
NCT06714942
Digital Intervention for Physical Activity
Auburn University
NCT07130734
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
NCT06442423
Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety
Michael J. Zvolensky, Ph.D.
NCT05288699
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
California Polytechnic State University-San Luis Obispo
NCT07477184
A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking
University of Houston
NCT06416059
Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System
University of Illinois at Chicago
NCT06555172
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care
Brigham and Women's Hospital
NCT07364825
Exploring Virtual Reality Adventure Training Exergaming
The University of Texas at Arlington
NCT05563805
Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students
Milton S. Hershey Medical Center
NCT07240792
Prediction of Anxiety and Memory State
Columbia University
NCT06551090
Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study
Birmingham VA Health Care System
NCT07288008
Teen Recovery Through Inspiration, Support, and Empowerment
University of Texas Southwestern Medical Center
NCT07170657
Enhancing Brain And Mental Health Through Breathing Practice
Mayo Clinic
NCT07369752
The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity
VA Office of Research and Development
NCT04953806
Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU
Mayo Clinic
NCT07351799
Recovery Through Inspiration, Support, and Empowerment
University of Texas Southwestern Medical Center
NCT07051200
Decoding and Modulating Affective Brain States
University of Pennsylvania
NCT05437705
Readiness and Progress in Emotion Regulation Therapy
Teachers College, Columbia University
NCT07478393
VR-PMR for Post-Burn Symptoms
Johns Hopkins University
NCT07317271
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
Stanford University
NCT07346638
Use of CBD in the Treatment of Anxiety
University of Florida
NCT06672666
Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.
Milton S. Hershey Medical Center
NCT04924244
Telehealth Collaborative Care Model (CoCM) in Lung Cancer
Abramson Cancer Center at Penn Medicine
NCT07102147
Effect of an Educational Nail Biopsy Video on Pre-operative Anxiety, Health Literacy, and Patient Satisfaction
Weill Medical College of Cornell University
NCT06274775
Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders
Rogers Behavioral Health
NCT07017322
IMST for Dementia Risk Reduction
Florida State University
NCT07349706
The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy
Dominican University New York
NCT06557083
Creatine for Depressed Male and Female Methamphetamine Users
Montana State University
NCT02568878
Lakota Family Acceptance Project
University of Michigan
NCT07326748
Focused Ultrasound for the Complex Patient
Washington D.C. Veterans Affairs Medical Center
NCT06453109
Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health
University of Florida
NCT05541887
ACT for HIV-Positive Men
University of Alabama at Birmingham
NCT06625437
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
M.D. Anderson Cancer Center
NCT06801041
Storytelling and Mindfulness for Graduate Student Wellbeing
University of Wisconsin, Madison
NCT05826860
Virtual Contexts for Affective Modulation
Trustees of Dartmouth College
NCT06986122
Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer
Cedars-Sinai Medical Center
NCT05086250
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Trustees of Dartmouth College
NCT06920238
Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia
Mclean Hospital
NCT04075435
taVNS for Anxiety in ASD
Medical University of South Carolina
NCT06258590
Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome
The Cooper Health System
NCT05719246
Mobile Cognitive Behavioral Therapy for Stroke
Weill Medical College of Cornell University
NCT06689878
The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety
Ohio State University
NCT05032105
The Community Youth Development Study: A Test of Communities That Care
University of Washington
NCT01088542
Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story
Baylor College of Medicine
NCT05809115
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 25 |
| Phase 3 | 6 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Trial Landscape
367 indexed Anxiety studies · 148 recruiting (40%).
Phase mix: 15 late (III/IV) vs 38 early (I/II).
Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety?
PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.