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ClinicalTrials.gov 148 recruiting now official registry

Anxiety clinical trials

148 of 367 indexed Anxiety trials are currently recruiting.

367 US clinical trials · 148 currently recruiting

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

The research picture

Anxiety has 367 registered US clinical trials, 148 of them open to new participants right now, about 40% of the total.

148
recruiting participants now
40%
of trials open to enrollment
15
in Phase 3–4 (later-stage)
11
top sponsor: University of California, Los Angeles
Phase 113Phase 225Phase 36Phase 49

Active & Recent Trials

367 total, page 3 of 8

RECRUITING NA 60 participants

Collaborative Care for Anxiety and Depression in Epilepsy

Wake Forest University Health Sciences

NCT05559749

RECRUITING NA 60 participants

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

Johns Hopkins University

NCT06341972

RECRUITING NA 55 participants

Neuromodulation of Brain and Emotional Responses to Psychological Stress

University of Pittsburgh

NCT06603064

RECRUITING NA 53 participants

Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students

University of Alabama, Tuscaloo

NCT07415460

RECRUITING NA 53 participants

Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments

University of South Dakota

NCT06789731

RECRUITING NA 51 participants

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

SF Research Institute

NCT06714942

RECRUITING NA 50 participants

Digital Intervention for Physical Activity

Auburn University

NCT07130734

RECRUITING Phase 1 50 participants

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

NCT06442423

RECRUITING NA 50 participants

Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety

Michael J. Zvolensky, Ph.D.

NCT05288699

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 50 participants

A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking

University of Houston

NCT06416059

RECRUITING NA 50 participants

Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System

University of Illinois at Chicago

NCT06555172

RECRUITING NA 45 participants

Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care

Brigham and Women's Hospital

NCT07364825

RECRUITING NA 40 participants

Exploring Virtual Reality Adventure Training Exergaming

The University of Texas at Arlington

NCT05563805

RECRUITING NA 40 participants

Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students

Milton S. Hershey Medical Center

NCT07240792

RECRUITING NA 40 participants

Prediction of Anxiety and Memory State

Columbia University

NCT06551090

RECRUITING NA 40 participants

Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study

Birmingham VA Health Care System

NCT07288008

RECRUITING NA 40 participants

Teen Recovery Through Inspiration, Support, and Empowerment

University of Texas Southwestern Medical Center

NCT07170657

RECRUITING NA 40 participants

Enhancing Brain And Mental Health Through Breathing Practice

Mayo Clinic

NCT07369752

RECRUITING NA 40 participants

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

VA Office of Research and Development

NCT04953806

RECRUITING NA 40 participants

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

Mayo Clinic

NCT07351799

RECRUITING NA 40 participants

Recovery Through Inspiration, Support, and Empowerment

University of Texas Southwestern Medical Center

NCT07051200

RECRUITING NA 40 participants

Decoding and Modulating Affective Brain States

University of Pennsylvania

NCT05437705

RECRUITING NA 36 participants

Readiness and Progress in Emotion Regulation Therapy

Teachers College, Columbia University

NCT07478393

RECRUITING NA 34 participants

VR-PMR for Post-Burn Symptoms

Johns Hopkins University

NCT07317271

RECRUITING NA 30 participants

The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

Stanford University

NCT07346638

RECRUITING Phase 2 30 participants

Use of CBD in the Treatment of Anxiety

University of Florida

NCT06672666

RECRUITING NA 30 participants

Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.

Milton S. Hershey Medical Center

NCT04924244

RECRUITING NA 30 participants

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

Abramson Cancer Center at Penn Medicine

NCT07102147

RECRUITING NA 30 participants

Effect of an Educational Nail Biopsy Video on Pre-operative Anxiety, Health Literacy, and Patient Satisfaction

Weill Medical College of Cornell University

NCT06274775

RECRUITING NA 30 participants

Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders

Rogers Behavioral Health

NCT07017322

RECRUITING NA 30 participants

IMST for Dementia Risk Reduction

Florida State University

NCT07349706

RECRUITING NA 30 participants

The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy

Dominican University New York

NCT06557083

RECRUITING Phase 3 29 participants

Creatine for Depressed Male and Female Methamphetamine Users

Montana State University

NCT02568878

RECRUITING NA 28 participants

Lakota Family Acceptance Project

University of Michigan

NCT07326748

RECRUITING NA 25 participants

Focused Ultrasound for the Complex Patient

Washington D.C. Veterans Affairs Medical Center

NCT06453109

RECRUITING NA 25 participants

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

University of Florida

NCT05541887

RECRUITING NA 24 participants

ACT for HIV-Positive Men

University of Alabama at Birmingham

NCT06625437

RECRUITING Phase 2 20 participants

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

M.D. Anderson Cancer Center

NCT06801041

RECRUITING NA 20 participants

Storytelling and Mindfulness for Graduate Student Wellbeing

University of Wisconsin, Madison

NCT05826860

RECRUITING NA 20 participants

Virtual Contexts for Affective Modulation

Trustees of Dartmouth College

NCT06986122

RECRUITING Early Phase 1 20 participants

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

NCT05086250

RECRUITING Phase 1 15 participants

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Trustees of Dartmouth College

NCT06920238

RECRUITING Early Phase 1 12 participants

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

Mclean Hospital

NCT04075435

RECRUITING NA 10 participants

taVNS for Anxiety in ASD

Medical University of South Carolina

NCT06258590

RECRUITING NA 10 participants

Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome

The Cooper Health System

NCT05719246

RECRUITING NA 10 participants

Mobile Cognitive Behavioral Therapy for Stroke

Weill Medical College of Cornell University

NCT06689878

RECRUITING Phase 1 10 participants

The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety

Ohio State University

NCT05032105

ACTIVE NOT RECRUITING NA 52,323 participants

The Community Youth Development Study: A Test of Communities That Care

University of Washington

NCT01088542

ACTIVE NOT RECRUITING 2,000 participants

Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

Baylor College of Medicine

NCT05809115

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anxiety Trial Landscape

367 indexed Anxiety studies · 148 recruiting (40%).

Phase mix: 15 late (III/IV) vs 38 early (I/II).

Top sponsor: University of California, Los Angeles (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anxiety?

PlainTrial tracks 367 US clinical trials for Anxiety, of which 148 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anxiety?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.