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ClinicalTrials.gov 148 recruiting now early-phase tilt #17 of 28,707 conditions

Anxiety: early-phase trial registry

148 of 367 indexed Anxiety trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #17 of 28,707 conditions by registered trial count.

367 US clinical trials · 148 currently recruiting · #17 of 28,707 conditions by registered trial count

Anxiety: 367 US clinical trials tracked, 148 recruiting.

Anxiety is the subject of 367 registered US clinical trials on ClinicalTrials.gov, 148 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Los Angeles, running 11 of these trials.

Enrollment posture brief

Registry condition anxiety

OPEN 148 | RECR 40% | LATE 15 | EARLY 38 | RANK #17 | SPON 11

Nearest open-share peer: Pain, Postoperative (40% recruiting · 114 trials)

Anxiety (this)40%Pain28.1%Diabetes25.1%Asthma18.5%Diabetes Mellitus, Type 217.9%
Open-enrollment share among volume-matched conditions near Anxiety

Anxiety lists 148 open slots (40% of 367 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety is recruiting above its size-band peers.

    148 of 367 indexed trials (40.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety trials is spread across many organizations.

    University of California, Los Angeles accounts for 11 of 367 trials (3%). 191 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety enrolment sits around 95 participants.

    Median target enrolment is 95 among the 365 trials that report a genuine target (sentinel values excluded). 188 of those (51.5%) plan for fewer than 100 participants.

  4. Anxiety research is mostly interventional.

    339 interventional and 28 observational studies make up this index (92.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 113Phase 225Phase 36Phase 49

Open and recent trials

367 total, page 3 of 8

RECRUITING NA 60 participants

Collaborative Care for Anxiety and Depression in Epilepsy

Wake Forest University Health Sciences

NCT05559749

RECRUITING NA 60 participants

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

Johns Hopkins University

NCT06341972

RECRUITING NA 55 participants

Neuromodulation of Brain and Emotional Responses to Psychological Stress

University of Pittsburgh

NCT06603064

RECRUITING NA 53 participants

Evaluating the Impact of SKY Breath Meditation on Stress, Well-being, and Connection in College Students

University of Alabama, Tuscaloo

NCT07415460

RECRUITING NA 53 participants

Mindfulness-Based Interventions Targeting First-Generation College Student Retention in Rural Environments

University of South Dakota

NCT06789731

RECRUITING NA 51 participants

Efficacy and Safety of a Proprietary Blend of Ashwagandha Root Extract (Aqueous) in Adult Men and Women With High Stress and Anxiety: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

SF Research Institute

NCT06714942

RECRUITING NA 50 participants

Digital Intervention for Physical Activity

Auburn University

NCT07130734

RECRUITING Phase 1 50 participants

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

NCT06442423

RECRUITING NA 50 participants

Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety

Michael J. Zvolensky, Ph.D.

NCT05288699

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 50 participants

A Mobile Intervention for Black Individuals Who Engage in Hazardous Drinking

University of Houston

NCT06416059

RECRUITING NA 50 participants

Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System

University of Illinois at Chicago

NCT06555172

RECRUITING NA 45 participants

Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care

Brigham and Women's Hospital

NCT07364825

RECRUITING NA 40 participants

Exploring Virtual Reality Adventure Training Exergaming

The University of Texas at Arlington

NCT05563805

RECRUITING NA 40 participants

Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students

Milton S. Hershey Medical Center

NCT07240792

RECRUITING NA 40 participants

Prediction of Anxiety and Memory State

Columbia University

NCT06551090

RECRUITING NA 40 participants

Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study

Birmingham VA Health Care System

NCT07288008

RECRUITING NA 40 participants

Teen Recovery Through Inspiration, Support, and Empowerment

University of Texas Southwestern Medical Center

NCT07170657

RECRUITING NA 40 participants

Enhancing Brain And Mental Health Through Breathing Practice

Mayo Clinic

NCT07369752

RECRUITING NA 40 participants

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

VA Office of Research and Development

NCT04953806

RECRUITING NA 40 participants

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

Mayo Clinic

NCT07351799

RECRUITING NA 40 participants

Recovery Through Inspiration, Support, and Empowerment

University of Texas Southwestern Medical Center

NCT07051200

RECRUITING NA 40 participants

Decoding and Modulating Affective Brain States

University of Pennsylvania

NCT05437705

RECRUITING NA 36 participants

Readiness and Progress in Emotion Regulation Therapy

Teachers College, Columbia University

NCT07478393

RECRUITING NA 34 participants

VR-PMR for Post-Burn Symptoms

Johns Hopkins University

NCT07317271

RECRUITING NA 30 participants

The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

Stanford University

NCT07346638

RECRUITING Phase 2 30 participants

Use of CBD in the Treatment of Anxiety

University of Florida

NCT06672666

RECRUITING NA 30 participants

Effect of Music on Pain and Anxiety in Chronic Pain Patients Undergoing Lumbar Interventional Procedures.

Milton S. Hershey Medical Center

NCT04924244

RECRUITING NA 30 participants

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

Abramson Cancer Center at Penn Medicine

NCT07102147

RECRUITING NA 30 participants

Effect of an Educational Nail Biopsy Video on Pre-operative Anxiety, Health Literacy, and Patient Satisfaction

Weill Medical College of Cornell University

NCT06274775

RECRUITING NA 30 participants

Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders

Rogers Behavioral Health

NCT07017322

RECRUITING NA 30 participants

IMST for Dementia Risk Reduction

Florida State University

NCT07349706

RECRUITING NA 30 participants

The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy

Dominican University New York

NCT06557083

RECRUITING Phase 3 29 participants

Creatine for Depressed Male and Female Methamphetamine Users

Montana State University

NCT02568878

RECRUITING NA 28 participants

Lakota Family Acceptance Project

University of Michigan

NCT07326748

RECRUITING NA 25 participants

Focused Ultrasound for the Complex Patient

Washington D.C. Veterans Affairs Medical Center

NCT06453109

RECRUITING NA 25 participants

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

University of Florida

NCT05541887

RECRUITING NA 24 participants

ACT for HIV-Positive Men

University of Alabama at Birmingham

NCT06625437

RECRUITING Phase 2 20 participants

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

M.D. Anderson Cancer Center

NCT06801041

RECRUITING NA 20 participants

Storytelling and Mindfulness for Graduate Student Wellbeing

University of Wisconsin, Madison

NCT05826860

RECRUITING NA 20 participants

Virtual Contexts for Affective Modulation

Trustees of Dartmouth College

NCT06986122

RECRUITING Early Phase 1 20 participants

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

Cedars-Sinai Medical Center

NCT05086250

RECRUITING Phase 1 15 participants

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Trustees of Dartmouth College

NCT06920238

RECRUITING Early Phase 1 12 participants

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

Mclean Hospital

NCT04075435

RECRUITING NA 10 participants

taVNS for Anxiety in ASD

Medical University of South Carolina

NCT06258590

RECRUITING NA 10 participants

Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome

The Cooper Health System

NCT05719246

RECRUITING NA 10 participants

Mobile Cognitive Behavioral Therapy for Stroke

Weill Medical College of Cornell University

NCT06689878

RECRUITING Phase 1 10 participants

The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety

Ohio State University

NCT05032105

ACTIVE NOT RECRUITING NA 52,323 participants

The Community Youth Development Study: A Test of Communities That Care

University of Washington

NCT01088542

ACTIVE NOT RECRUITING 2,000 participants

Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

Baylor College of Medicine

NCT05809115

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Phase Distribution

PhaseTrial count
Phase 1 13
Phase 2 25
Phase 3 6
Phase 4 9

Named interventions

Most-linked intervention names on Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
13 trials
Placebo Other
7 trials
Music Other
4 trials
Yoga Behavioral
3 trials
Psilocybin Drug
3 trials
Cognitive Behavioral Therapy (CBT) Behavioral
3 trials
IDgenetix Neuropsychiatric Test Panel Genetic
2 trials
Emotion Regulation Therapy via Telehealth Behavioral
2 trials

US sites by state

Facility locations filed on Anxiety trials. A trial with sites in several states counts in each.

California 58 trials
New York 38 trials
Massachusetts 30 trials
Texas 27 trials
Florida 27 trials
Pennsylvania 24 trials
North Carolina 22 trials
Ohio 21 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety page

367 registered trials, 148 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety condition card totals 367 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.