Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04657432 · ClinicalTrials.gov registry record · NA

Brief, High-dose rTMS for Depression

A NA study of Depression and Anxiety, sponsored by Medical University of South Carolina.

Active
Registry status
NA
Development phase
70
Enrollment target
1
Study location

NCT04657432 is a NA study of Depression and Anxiety that is active but no longer recruiting, run by Medical University of South Carolina. The registered enrollment target is 70 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04657432, a NA study of Depression and Anxiety, is active but no longer recruiting, sponsored by Medical University of South Carolina.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on rational decision trees for dosage determination. The purpose of this study is to systematically examine an accelerated protocol of intermittent theta burst (iTBS). Study 1 aims to provide a quantifiable dose-response curve for iTBS and depressive symptom reduction in major depression. Study 2 aims to determine the role of individual variations of their functional networks compared to the site of stimulation and clinical outcomes.

Conditions Studied

Interventions

  • DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)

Study Locations (1)

South Carolina

  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2021-05-25
Est. Completion 2026-12-01
Phase NA

What the Registry Record Tells You About NCT04657432

The ClinicalTrials.gov registry entry for NCT04657432 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.

NCT04657432 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT04657432 about?

NCT04657432 is a clinical study titled "Brief, High-dose rTMS for Depression". High frequency repetitive transcranial magnetic stimulation (rTMS) has been shown to be safe, feasible, and acceptable. Conventionally, rTMS investigations have relied on rational decision trees for dosage determination. The purpose of this study is to systematically examine an accelerated protocol ...

What is the current status of trial NCT04657432?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2021-05-25. Estimated completion is 2026-12-01.

What conditions does trial NCT04657432 study?

This clinical trial studies the following conditions: Depression, Anxiety.

What interventions are being tested in trial NCT04657432?

The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).

Who is sponsoring clinical trial NCT04657432?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04657432 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.