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NCT06986122 · ClinicalTrials.gov registry record · NA
Virtual Contexts for Affective Modulation
A NA study of Anxiety and Memory, sponsored by Trustees of Dartmouth College.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06986122 is a NA study of Anxiety and Memory that is actively recruiting participants, run by Trustees of Dartmouth College. The registered enrollment target is 20 participants, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06986122, a NA study of Anxiety and Memory, is actively recruiting participants, sponsored by Trustees of Dartmouth College.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study investigates how spatial context and perceived controllability modulate pain, affective states such as anxiety, and motivated behavior. The study examines how control over pain and threat-related environments influences pain perception, state anxiety, associated autonomic responses, and behavior. The main questions it aims to answer are: Does having control over pain within specific contexts alter how much pain people feel-even when the stimulus intensity remains constant? How do different types of environments (safe, controllable, or uncontrollable) shape pain-related brain activity, subjective anxiety, and physiological arousal? How do people perform cognitively demanding or distracting tasks (and retain their memory) when under threat versus when in control? Lastly, how do these learned associations with spatial contexts persist or adapt when environmental contingencies are explicitly changed? Taken together, exploration of these factors may lay the groundwork for understanding how placebo-related mechanisms-including perceived control, contextual learning, emotional engagement, and distraction-interact to shape pain and anxiety in complex environments.
Conditions Studied
Interventions
- BEHAVIORAL Pain Threat Manipulation
- BEHAVIORAL Pain Controllability Manipulation
Study Locations (1)
New Hampshire
- Dartmouth College - Hanover
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-10-28 |
| Est. Completion | 2029-06-15 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06986122
The ClinicalTrials.gov registry entry for NCT06986122 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (95% lower). The listed sponsor is Trustees of Dartmouth College, which has 31 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Anxiety appearing as the primary indexed condition, and to 2 interventions - of which Pain Threat Manipulation is the first listed.
NCT06986122 reports 1 study location spanning 1 distinct geographic area - top geographies include New Hampshire.
Frequently Asked Questions
What is clinical trial NCT06986122 about?
NCT06986122 is a clinical study titled "Virtual Contexts for Affective Modulation". This study investigates how spatial context and perceived controllability modulate pain, affective states such as anxiety, and motivated behavior. The study examines how control over pain and threat-related environments influences pain perception, state anxiety, associated autonomic responses, and b...
What is the current status of trial NCT06986122?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-10-28. Estimated completion is 2029-06-15.
What conditions does trial NCT06986122 study?
This clinical trial studies the following conditions: Anxiety, Memory, Pain Control.
What interventions are being tested in trial NCT06986122?
The interventions under investigation include: Pain Threat Manipulation (BEHAVIORAL), Pain Controllability Manipulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06986122?
This trial is sponsored by Trustees of Dartmouth College, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06986122 being conducted?
This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.