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NCT06453109 · ClinicalTrials.gov registry record · NA

Focused Ultrasound for the Complex Patient

A NA study of Anxiety and Opioid Use Disorder, sponsored by Washington D.C. Veterans Affairs Medical Center.

Recruiting
Registry status
NA
Development phase
25
Enrollment target
1
Study location

NCT06453109 is a NA study of Anxiety and Opioid Use Disorder that is actively recruiting participants, run by Washington D.C. Veterans Affairs Medical Center. The registered enrollment target is 25 participants, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06453109, a NA study of Anxiety and Opioid Use Disorder, is actively recruiting participants, sponsored by Washington D.C. Veterans Affairs Medical Center.

RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI in pain processing, anxiety, and opiate cue-induced craving. The main question\[s\] it aims to answer are: * the safety and tolerability of LIFU delivered bilaterally to AI compared to sham stimulation in individuals with opiate use disorder (OUD), anxiety, and chronic back pain * the effects of LIFU vs sham on measures of pain processing, anxiety symptoms, and opiate cue-induced craving Participants will undergo anatomical MRI, neurological assessment, clinical assessment and patient query to assess the safety and tolerability of LIFU vs sham.

Interventions

  • DEVICE low intensity focused ultrasound (LIFU)

Study Locations (1)

District of Columbia

  • Washington DC Veterans Affairs Medical Center - Washington D.C.

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2024-04-29
Est. Completion 2025-09-30
Phase NA

What the Registry Record Tells You About NCT06453109

The ClinicalTrials.gov registry entry for NCT06453109 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 364 other Anxiety trials with a reported enrollment target (94% lower). The listed sponsor is Washington D.C. Veterans Affairs Medical Center, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Anxiety appearing as the primary indexed condition, and to 1 intervention - of which low intensity focused ultrasound (LIFU) is the first listed.

NCT06453109 reports 1 study location spanning 1 distinct geographic area - top geographies include District of Columbia.

Frequently Asked Questions

What is clinical trial NCT06453109 about?

NCT06453109 is a clinical study titled "Focused Ultrasound for the Complex Patient". The goal of this clinical trial is to to inhibit the anterior insula (AI) with low intensity focused ultrasound (LIFU) to determine the causal role for the AI in pain processing, anxiety, and opiate cue-induced craving. The main question\[s\] it aims to answer are: * the safety and tolerability of ...

What is the current status of trial NCT06453109?

This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2024-04-29. Estimated completion is 2025-09-30.

What conditions does trial NCT06453109 study?

This clinical trial studies the following conditions: Anxiety, Opioid Use Disorder, Chronic Back Pain.

What interventions are being tested in trial NCT06453109?

The interventions under investigation include: low intensity focused ultrasound (LIFU) (DEVICE).

Who is sponsoring clinical trial NCT06453109?

This trial is sponsored by Washington D.C. Veterans Affairs Medical Center, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06453109 being conducted?

This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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