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NCT06603064 · ClinicalTrials.gov registry record · NA
Neuromodulation of Brain and Emotional Responses to Psychological Stress
A NA study of Healthy and Anxiety, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 55
- Enrollment target
- 1
- Study location
NCT06603064: Recruiting NA study of Healthy and Anxiety, sponsored by University of Pittsburgh.
NCT06603064 is a NA study of Healthy and Anxiety that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 55 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06603064, a NA study of Healthy and Anxiety, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators are conducting this study to test if temporarily and non-invasively stimulating the brain will affect the emotional response to stress in healthy participants. Participants will perform a series of tasks while completing an MRI scan. After this, participants will be randomized to undergo transcranial magnetic stimulation (TMS) at two visits, undergoing active stimulation at one visit and undergoing 'sham' stimulation at another visit. Immediately following both stimulation sessions, participants will repeat the tasks during MRI scanning.
Primary Outcome
Blood-oxygen-level-dependent (BOLD) signal in a dorsal anterior cingulate cortex (dACC) region of interest mask extracted from the incongruent (stress) vs congruent (control) contrast.
Interventions
- DEVICE Active continuous theta burst stimulation
- DEVICE Sham continuous theta burst stimulation
Study Locations (1)
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2025-04-09 |
| Est. Completion | 2029-07 |
| Phase | NA |
What NCT06603064 shows while recruiting
NCT06603064 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Active continuous theta burst stimulation is the first listed.
NCT06603064 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06603064 about?
NCT06603064 is a clinical study titled "Neuromodulation of Brain and Emotional Responses to Psychological Stress". Investigators are conducting this study to test if temporarily and non-invasively stimulating the brain will affect the emotional response to stress in healthy participants. Participants will perform a series of tasks while completing an MRI scan. After this, participants will be randomized to unde...
What is the current status of trial NCT06603064?
This trial is currently recruiting. It is a NA study. The enrollment target is 55 participants. The study started on 2025-04-09. Estimated completion is 2029-07.
What conditions does trial NCT06603064 study?
This clinical trial studies the following conditions: Healthy, Anxiety.
What interventions are being tested in trial NCT06603064?
The interventions under investigation include: Active continuous theta burst stimulation (DEVICE), Sham continuous theta burst stimulation (DEVICE).
Who is sponsoring clinical trial NCT06603064?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06603064 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06603064's enrollment target sits among peer trials
55 427th of 1090 higher than 659 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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