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NCT06380517 · ClinicalTrials.gov registry record · Phase 3
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
A Phase 3 study of Amblyopia, sponsored by Jaeb Center for Health Research.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 238
- Enrollment target
- 20
- Study locations
NCT06380517: Recruiting Phase 3 study of Amblyopia, sponsored by Jaeb Center for Health Research.
NCT06380517 is a Phase 3 study of Amblyopia that is actively recruiting participants, run by Jaeb Center for Health Research. The registered enrollment target is 238 participants, above the 156-participant average among 24 other Amblyopia trials with a reported enrollment target (53% higher). The trial reports 20 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06380517, a Phase 3 study of Amblyopia, is actively recruiting participants, sponsored by Jaeb Center for Health Research.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 238 participants
- Enrollment target
- 20
- Study locations
Study Summary
In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days per week with respect to change in amblyopic eye distance VA from randomization to 26 weeks.
Conditions Studied
Interventions
- DEVICE Luminopia
- OTHER Eye Patch
Study Locations (20)
California
- Univ. of California- Berkeley - Berkeley
- Southern California College of Optometry - Fullerton
- Univ of California, Irvine- Gavin Herbert Eye Institute - Irvine
- Children's Hospital of Los Angeles (CHLA) - Los Angeles
- Jules Stein Eye Institute at the University of California, Los Angeles - Los Angeles
- Stanford University - Palo Alto
- Western University College of Optometry - Pomona
- University of California, Davis - Sacramento
- Rady Children's Hospital - San Diego Dept of Ophthalmology - San Diego
- University of California San Francisco Department of Ophthalmology - San Francisco
Arizona
- Midwestern University Eye Institute - Glendale
- Phoenix Children's Medical Group - Ophthalmology - Scottsdale
- University of Arizona - Tucson
Arkansas
- Arkansas Childrens - Little Rock
- McFarland Eye Care Center - Little Rock
Alabama
- UAB Pediatric Eye Care; Birmingham Health Care - Birmingham
Connecticut
- Yale University - New Haven
Florida
- University of South Florida (USF) Eye - Tampa
Georgia
- The Emory Eye Center - Atlanta
Illinois
- Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 238 participants |
| Start Date | 2024-07-01 |
| Est. Completion | 2028-01-01 |
| Phase | Phase 3 |
What NCT06380517 shows while recruiting
NCT06380517 is an interventional study that assigns participants to a tested intervention. The registered 238 participants enrollment target is mid-sized for trials with a published cap, above the 156-participant average among 24 other Amblyopia trials with a reported enrollment target (53% higher).
The record links to 1 condition, with Amblyopia appearing as the primary indexed condition, and to 2 interventions - of which Luminopia is the first listed.
NCT06380517 names 20 study sites across 8 states, led by California, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT06380517 about?
NCT06380517 is a clinical study titled "Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age". In children 4 to 7 years of age, to determine if treatment with 1 hour per day 6 days per week of watching dichoptic movies/shows wearing the Luminopia headset is non-inferior to treatment with 2 hours of patching per day 7 days per week with respect to change in amblyopic eye distance VA from rando...
What is the current status of trial NCT06380517?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 238 participants. The study started on 2024-07-01. Estimated completion is 2028-01-01.
What conditions does trial NCT06380517 study?
This clinical trial studies the following conditions: Amblyopia.
What interventions are being tested in trial NCT06380517?
The interventions under investigation include: Luminopia (DEVICE), Eye Patch (OTHER).
Who is sponsoring clinical trial NCT06380517?
This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06380517 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amblyopia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06380517's enrollment target sits among peer trials
238 6th of 24 higher than 19 of 24 other Amblyopia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amblyopia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
RECRUITING · Phase 3
-
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
RECRUITING · Phase 3
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Amblyopia (Lazy Eye) Treatment Study
COMPLETED · Phase 3
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Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children
COMPLETED · Phase 3
-
Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
COMPLETED · Phase 3
-
Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia
COMPLETED · Phase 3
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