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2026 data Public-data reference. official source

Basal Cell Carcinoma

Open-data reference.

25 US clinical trials · 13 currently recruiting

Active & Recent Trials

RECRUITING Phase 1 115 participants

A Beta-only IL-2 ImmunoTherapY Study

Medicenna Therapeutics

NCT05086692

RECRUITING Phase 1 90 participants

Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies

Replimune

NCT04349436

RECRUITING Phase 2 80 participants

To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma

Stamford Pharmaceuticals

NCT06344052

RECRUITING NA 60 participants

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

Roswell Park Cancer Institute

NCT07182240

RECRUITING Phase 2 57 participants

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03521830

RECRUITING Phase 1 56 participants

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

Memorial Sloan Kettering Cancer Center

NCT05859074

RECRUITING NA 52 participants

Investigation of Standard Excision Surgical Margins Using Two Photon Fluorescence Microscopy

University of Rochester

NCT06473103

RECRUITING NA 40 participants

Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

Christopher Zachary

NCT04744935

RECRUITING Phase 2 30 participants

Neoadjuvant Nivolumab + Relatlimab (Opdualag) Versus Nivolumab for Resectable High-Risk Basal Cell Carcinoma

University of California, San Diego

NCT06624475

RECRUITING Phase 2 28 participants

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

Case Comprehensive Cancer Center

NCT05020912

RECRUITING Phase 2 27 participants

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Mayo Clinic

NCT07285044

RECRUITING 20 participants

Raman Spectroscopy and Skin Cancer

Renee Farrell

NCT06384924

RECRUITING Early Phase 1 10 participants

CivaDerm(TM) Surface Therapy Pilot Study

CivaTech Oncology

NCT04480645

ACTIVE NOT RECRUITING Phase 2 38 participants

A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma

Memorial Sloan Kettering Cancer Center

NCT05294120

ACTIVE NOT RECRUITING 26 participants

A Study of Observation and Follow-up in People With Basal Cell Carcinoma

Memorial Sloan Kettering Cancer Center

NCT05473507

ACTIVE NOT RECRUITING Phase 1 25 participants

Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II)

SkinJect

NCT04928222

COMPLETED 1,111 participants

DERM US and EU Validation Study

Skin Analytics Limited

NCT05126173

COMPLETED 187 participants

Electronic Brachytherapy for the Treatment of NMSC

Xoft

NCT01016899

COMPLETED 180 participants

Does Cryofixation of Skin Specimens Affect Quality of Subsequent Formalin Fixed Paraffin Embedded H and E Histology

Abramson Cancer Center at Penn Medicine

NCT01540695

COMPLETED NA 75 participants

Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery

Mayo Clinic

NCT00578214

COMPLETED Phase 4 49 participants

Intron-A/Aldara Combination Therapy for Basal Cell Carcinoma (BCC)

The University of Texas Health Science Center, Houston

NCT00581425

COMPLETED 45 participants

Reflectance Confocal Microscopy of Wounds During Moh's Surgery: Feasibility Testing of a Mosaicing Algorithm for Intraoperative Imaging of Cancer Margins

Memorial Sloan Kettering Cancer Center

NCT01872130

COMPLETED Phase 2 40 participants

Photochemical Tissue Bonding

Massachusetts General Hospital

NCT00586040

COMPLETED Phase 2 32 participants

Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With Basal Cell Carcinoma

Sirnaomics

NCT04669808

COMPLETED NA 32 participants

Video-Based Treatment Options for Basal Cell Carcinoma

Emory University

NCT02158650

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 8
Phase 4 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Basal Cell Carcinoma Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Basal Cell Carcinoma, and 13 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Basal Cell Carcinoma shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Basal Cell Carcinoma is led by Memorial Sloan Kettering Cancer Center with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Basal Cell Carcinoma?

PlainTrial tracks 25 US clinical trials for Basal Cell Carcinoma, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Basal Cell Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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