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NCT06712849 · ClinicalTrials.gov registry record · NA
Noninvasive Brain Stimulation in Adult Amblyopia
A NA study of Amblyopia, sponsored by Midwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06712849: Recruiting NA study of Amblyopia, sponsored by Midwestern University.
NCT06712849 is a NA study of Amblyopia that is actively recruiting participants, run by Midwestern University. The registered enrollment target is 60 participants, below the 163-participant average among 24 other Amblyopia trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06712849, a NA study of Amblyopia, is actively recruiting participants, sponsored by Midwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare baseline measurements of crowded visual acuity, contrast sensitivity, stereoacuity, phosphene thresholds, global motion perception, form pattern recognition and pattern-reversal visual evoked potentials (VEPs) to post-treatment measurements for each group.
Primary Outcome
A change in crowded visual acuity is measured in LogMAR from baseline.
Conditions Studied
Interventions
- DEVICE Sham Transcranial Random Noise Stimulation
- DEVICE High Frequency Transcranial Random Noise Stimulation
Study Locations (1)
Illinois
- Midwestern University Eye Institute - Downers Grove
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-05-01 |
| Est. Completion | 2028-12-31 |
| Phase | NA |
What NCT06712849 shows while recruiting
NCT06712849 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 163-participant average among 24 other Amblyopia trials with a reported enrollment target (63% lower).
The record links to 1 condition, with Amblyopia appearing as the primary indexed condition, and to 2 interventions - of which Sham Transcranial Random Noise Stimulation is the first listed.
NCT06712849 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06712849 about?
NCT06712849 is a clinical study titled "Noninvasive Brain Stimulation in Adult Amblyopia". The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of ad...
What is the current status of trial NCT06712849?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-05-01. Estimated completion is 2028-12-31.
What conditions does trial NCT06712849 study?
This clinical trial studies the following conditions: Amblyopia.
What interventions are being tested in trial NCT06712849?
The interventions under investigation include: Sham Transcranial Random Noise Stimulation (DEVICE), High Frequency Transcranial Random Noise Stimulation (DEVICE).
Who is sponsoring clinical trial NCT06712849?
This trial is sponsored by Midwestern University, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06712849 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amblyopia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06712849's enrollment target sits among peer trials
60 18th of 24 higher than 7 of 24 other Amblyopia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amblyopia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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