Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06049459 · ClinicalTrials.gov registry record · NA
Novel Amblyopia Treatment With Virtual Reality Games
A NA study of Amblyopia, sponsored by Marjean Ku.
- Recruiting
- Registry status
- NA
- Development phase
- 8
- Enrollment target
- 1
- Study location
NCT06049459: Recruiting NA study of Amblyopia, sponsored by Marjean Ku.
NCT06049459 is a NA study of Amblyopia that is actively recruiting participants, run by Marjean Ku. The registered enrollment target is 8 participants, below the 165-participant average among 24 other Amblyopia trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06049459, a NA study of Amblyopia, is actively recruiting participants, sponsored by Marjean Ku.
- RECRUITING
- Registry status
- NA
- Development phase
- 8 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years. The main question it aims to answer is: Is a 16-week course of amblyopia treatment using Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for approx. 25 min/day, 6 days/week more effective for improvement in amblyopic-eye VA, binocularity (stereoacuity, suppression, alignment), contrast sensitivity, attention, oculomotor function, visual-motor integration, and quality of life than 16 weeks of continued glasses alone? Participants will each serve as their own control and complete: Treatment period 1: Continued optical correction (glasses) alone for 16 weeks; Treatment period 2: Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for 16 weeks (approx. 25min/day, 6 days/week) plus continued optical correction
Primary Outcome
Optical correction worn for testing using Amblyopia Treatment Study (ATS) protocol; HOTV for ages 5-6 years; E-ETDRS for ages 7 years and older
Conditions Studied
Interventions
- DEVICE Optical Correction
- DEVICE Therapeutic Dichoptic Virtual Reality Games
Study Locations (1)
Ohio
- The Ohio State University College of Optometry - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2024-03-14 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06049459 shows while recruiting
NCT06049459 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 165-participant average among 24 other Amblyopia trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Amblyopia appearing as the primary indexed condition, and to 2 interventions - of which Optical Correction is the first listed.
NCT06049459 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06049459 about?
NCT06049459 is a clinical study titled "Novel Amblyopia Treatment With Virtual Reality Games". The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years. The main question it aims to answer is: Is a 16-week course of amblyopia treatment using Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for appr...
What is the current status of trial NCT06049459?
This trial is currently recruiting. It is a NA study. The enrollment target is 8 participants. The study started on 2024-03-14. Estimated completion is 2026-12-31.
What conditions does trial NCT06049459 study?
This clinical trial studies the following conditions: Amblyopia.
What interventions are being tested in trial NCT06049459?
The interventions under investigation include: Optical Correction (DEVICE), Therapeutic Dichoptic Virtual Reality Games (DEVICE).
Who is sponsoring clinical trial NCT06049459?
This trial is sponsored by Marjean Ku, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06049459 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amblyopia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06049459's enrollment target sits among peer trials
8 25th of 24 the lowest of 24 other Amblyopia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amblyopia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Noninvasive Brain Stimulation in Adult Amblyopia
RECRUITING · NA
-
OCT Eccentric Fixation and Amblyopia in Children
RECRUITING · NA
-
Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games
RECRUITING · NA
-
Patch-free Occlusion Therapy
RECRUITING · NA
-
Amblyopia Treatment for Children Aged 8 to 12 Years
RECRUITING · NA
-
Binocular Amblyopia Treatment
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI