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NCT03109314 · ClinicalTrials.gov registry record · Phase 4

Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia

A Phase 4 study of Amblyopia, sponsored by Dennis Levi.

Completed
Registry status
Phase 4
Development phase
20
Enrollment target
1
Study location

NCT03109314 is a Phase 4 study of Amblyopia that has completed, run by Dennis Levi. The registered enrollment target is 20 participants, below the 165-participant average among 24 other Amblyopia trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03109314, a Phase 4 study of Amblyopia, has completed, sponsored by Dennis Levi.

COMPLETED
Registry status
Phase 4
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The research deals with amblyopia or lazy eye, a condition that affects about 3% of the population, and results in a variety of visual deficits. Recent work suggests that there is limited neural plasticity in the visual system of adults with amblyopia. This study is aimed at understanding and increasing this plasticity. In this study, the investigators aim to understand how the amblyopic brain learns and how this process is affected by a drug called donepezil, which is sometimes given as a treatment for Alzheimer's disease. The investigators hope that this study will help to identify the chemical components that help the brain to learn, as well as the mechanism of amblyopia. The investigators also plan to test the normal periphery, as control.

Conditions Studied

Interventions

  • DRUG Donepezil
  • BEHAVIORAL Single-letter training
  • BEHAVIORAL Uncrowd training

Study Locations (1)

California

  • University of California, Berkeley - Berkeley

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2012-05-01
Est. Completion 2018-12-01
Phase Phase 4

Sponsor

Dennis Levi

1 total trials

What the Registry Record Tells You About NCT03109314

The ClinicalTrials.gov registry entry for NCT03109314 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 165-participant average among 24 other Amblyopia trials with a reported enrollment target (88% lower). The listed sponsor is Dennis Levi, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Amblyopia appearing as the primary indexed condition, and to 3 interventions - of which Donepezil is the first listed.

NCT03109314 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03109314 about?

NCT03109314 is a clinical study titled "Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia". The research deals with amblyopia or lazy eye, a condition that affects about 3% of the population, and results in a variety of visual deficits. Recent work suggests that there is limited neural plasticity in the visual system of adults with amblyopia. This study is aimed at understanding and increa...

What is the current status of trial NCT03109314?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2012-05-01. Estimated completion is 2018-12-01.

What conditions does trial NCT03109314 study?

This clinical trial studies the following conditions: Amblyopia.

What interventions are being tested in trial NCT03109314?

The interventions under investigation include: Donepezil (DRUG), Single-letter training (BEHAVIORAL), Uncrowd training (BEHAVIORAL).

Who is sponsoring clinical trial NCT03109314?

This trial is sponsored by Dennis Levi, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03109314 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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