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ClinicalTrials.gov 6 recruiting now official registry

ALL clinical trials

Every US clinical trial registered for ALL — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

11 US clinical trials · 6 currently recruiting

The research picture

ALL has 11 registered US clinical trials, 6 of them open to new participants right now — about 55% of the total.

6
recruiting participants now
55%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: National Cancer Institute (NCI)

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,000 participants

A Long Term Follow-up Study of TScan TCR-T Products

TScan Therapeutics

NCT06976736

RECRUITING Phase 1 54 participants

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

NCT05476770

RECRUITING Phase 1 50 participants

UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy

University of Alabama at Birmingham

NCT06047886

RECRUITING Phase 2 31 participants

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Memorial Sloan Kettering Cancer Center

NCT04644016

RECRUITING 30 participants

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

Children's Hospital Medical Center, Cincinnati

NCT06131801

RECRUITING Phase 1 15 participants

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

University of Chicago

NCT03571321

ACTIVE NOT RECRUITING NA 44 participants

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT05550948

ACTIVE NOT RECRUITING Phase 1 23 participants

Venetoclax Plus Inotuzumab for B-ALL

Dana-Farber Cancer Institute

NCT05016947

COMPLETED Phase 1 134 participants

Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies

National Cancer Institute (NCI)

NCT02315612

COMPLETED Early Phase 1 30 participants

Pilot Study of Non-Myeloablative, HLA-Matched Allogeneic Stem Cell Transplantation for Pediatric Hematopoietic Malignancies

National Cancer Institute (NCI)

NCT00013533

COMPLETED NA 23 participants

Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With ALL

Ann & Robert H Lurie Children's Hospital of Chicago

NCT02133599

Reading the ALL Trial Landscape

ClinicalTrials.gov lists 11 US studies indexed under ALL, and 6 of those are currently open to recruitment — roughly 55% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for ALL shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for ALL is led by National Cancer Institute (NCI) with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for ALL?

PlainTrial tracks 11 US clinical trials for ALL, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for ALL?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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