Therapeutic Advances in Childhood Leukemia Consortium

19 total trials 2 currently recruiting 8 completed

Therapeutic Advances in Childhood Leukemia Consortium sponsors 19 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 8 completed. 0 of these trials are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Lymphoblastic Leukemia, Acute, Childhood, with 2 trials.

Trial Pipeline

19 total, page 1 of 1

RECRUITING Phase 1

A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

NCT05849662

RECRUITING Phase 1

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

NCT05476770

ACTIVE NOT RECRUITING Phase 1

PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

NCT03817320

COMPLETED Phase 1

Epigenetic Reprogramming in Relapse/Refractory AML

NCT03263936

COMPLETED Phase 1

Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

NCT02879643

COMPLETED Phase 1

A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma

NCT01614197

TERMINATED Phase 1

Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

NCT01743807

COMPLETED Phase 1

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

NCT01861002

TERMINATED Phase 1

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

NCT01483690

COMPLETED Phase 1

AC220 for Children With Relapsed/Refractory ALL or AML

NCT01411267

COMPLETED Phase 1

A Study Of Panobinostat In Children With Refractory Hematologic Malignancies

NCT01321346

TERMINATED Phase 1

EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)

NCT01186328

TERMINATED Phase 2

Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia

NCT01158885

TERMINATED Phase 1

Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL

NCT00981799

COMPLETED Phase 1

Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.

NCT01041508

TERMINATED Phase 2

T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML)

NCT00939653

TERMINATED Phase 1

Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)

NCT00928200

COMPLETED Phase 1

Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

NCT00440726

TERMINATED Phase 1

ABT-751 With Chemotherapy for Relapsed Pediatric ALL

NCT00439296

What the Pipeline for Therapeutic Advances in Childhood Leukemia Consortium Shows

According to the ClinicalTrials.gov registry, Therapeutic Advances in Childhood Leukemia Consortium is linked to 19 US clinical trials across every stage of research activity. Of those, 2 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 8 are already marked complete, representing roughly 42% of the total.

The phase mix for Therapeutic Advances in Childhood Leukemia Consortium reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 19 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Therapeutic Advances in Childhood Leukemia Consortium is Lymphoblastic Leukemia, Acute, Childhood with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.