Genzyme, a Sanofi Company

196 total trials 4 currently recruiting 159 completed

Genzyme, a Sanofi Company sponsors 196 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 159 completed. 65 of these trials are in Phase 3-4 (later-stage) and 114 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Glycogen Storage Disease Type II (GSD-II), with 5 trials.

Trial Pipeline

196 total, page 1 of 4

RECRUITING

Pompe Pregnancy Sub-Registry

NCT00567073

RECRUITING

Pompe Disease Registry Protocol

NCT00231400

RECRUITING

Fabry Disease Registry & Pregnancy Sub-registry

NCT00196742

RECRUITING

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

NCT00358943

ACTIVE NOT RECRUITING Phase 3

Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B

NCT03974113

ACTIVE NOT RECRUITING Phase 3

Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX

NCT03754790

ACTIVE NOT RECRUITING Phase 2

A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa

NCT03019406

ACTIVE NOT RECRUITING Phase 2

Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension

NCT02843035

TERMINATED Phase 3

A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2

NCT04221451

TERMINATED Phase 2

Study of Lademirsen (SAR339375) in Patients With Alport Syndrome

NCT02855268

COMPLETED Phase 4

Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada

NCT03784898

COMPLETED Phase 1

Effect of Venglustat in Patients With Renal Impairment

NCT03687554

TERMINATED Phase 2

A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

NCT03523728

COMPLETED Phase 1

A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants

NCT06421714

COMPLETED Phase 3

A Study of Fitusiran in Severe Hemophilia A and B Patients Previously Receiving Factor or Bypassing Agent Prophylaxis

NCT03549871

COMPLETED Phase 3

A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors

NCT03417245

COMPLETED Phase 3

A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors

NCT03417102

COMPLETED Phase 1

A Study of RG-012 in Subjects With Alport Syndrome

NCT03373786

TERMINATED Phase 2

A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation

NCT02906020

COMPLETED Phase 3

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

NCT02782741

COMPLETED Phase 2

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

NCT02004691

COMPLETED Phase 1

An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemophilia A or B

NCT02554773

COMPLETED

LEMTRADA Pregnancy Registry in Multiple Sclerosis

NCT03774914

COMPLETED Phase 1

A Study of the Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate

NCT02536911

COMPLETED Phase 2

Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Naïve Adult Male Patients With Fabry Disease

NCT02489344

COMPLETED Phase 1

Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency

NCT02292654

COMPLETED Phase 1

Taste Evaluation of Different Liquid Formulations With Eliglustat

NCT02422654

COMPLETED

Alglucosidase Alfa Pompe Safety Sub-Registry

NCT01710813

TERMINATED Phase 2

Efficacy and Safety of Vatelizumab in Patients Who Completed Treatment in Study DRI13839

NCT02306811

COMPLETED Phase 4

Phase IIIB-IV Long-Term Follow-up Study for Patients Who Participated in CAMMS03409

NCT02255656

COMPLETED Phase 4

Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease

NCT01410890

COMPLETED Phase 2

Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-naïve Adult Male Patients With Fabry Disease

NCT02228460

COMPLETED

ATHENA: Natural History of Disease Study in Alport Syndrome Patients

NCT02136862

TERMINATED Phase 2

Efficacy and Safety of Vatelizumab in Patients With Relapsing-Remitting Multiple Sclerosis

NCT02222948

COMPLETED Phase 3

Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Sclerosis

NCT02201108

COMPLETED Phase 2

Avalglucosidase Alfa Extension Study

NCT02032524

COMPLETED Phase 2

A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

NCT02004704

COMPLETED Phase 3

Evaluation of Efficacy, Safety of Vandetanib in Patients With Differentiated Thyroid Cancer

NCT01876784

COMPLETED Phase 1

Safety and Efficacy Evaluation of Repeat neoGAA Dosing in Late Onset Pompe Disease Patients.

NCT01898364

TERMINATED Phase 1

A Study of Renal Function in Treatment-naïve, Young Male Patients With Fabry Disease

NCT01839526

COMPLETED Phase 1

Tolerability and Safety Study of Recombinant Human Acid Sphingomyelinase in Acid Sphingomyelinase Deficiency Patients

NCT01722526

COMPLETED Phase 1

A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of Genz-682452 in Healthy Volunteers

NCT01710826

COMPLETED NA

A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis of the Hip

NCT01618708

COMPLETED Phase 1

Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men

NCT01674036

COMPLETED Phase 2

A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)

NCT01665391

TERMINATED Phase 4

A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Patients With Infantile-Onset Pompe Disease

NCT01597596

COMPLETED Phase 1

Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in Healthy Adults

NCT01659944

COMPLETED Phase 2

An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease

NCT01574326

COMPLETED Phase 4

A Study Evaluating Glycosphingolipid Clearance in Patients Treated With Agalsidase Alfa Who Switch to Agalsidase Beta

NCT01650779

COMPLETED

Pompe Lactation Sub-Registry

NCT00566878

Page 1 of 4 Next →

What the Pipeline for Genzyme, a Sanofi Company Shows

According to the ClinicalTrials.gov registry, Genzyme, a Sanofi Company is linked to 196 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting, about 2% of the sponsor's indexed portfolio, and 159 are already marked complete, representing roughly 81% of the total.

The phase mix for Genzyme, a Sanofi Company reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 114 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Genzyme, a Sanofi Company is Glycogen Storage Disease Type II (GSD-II) with 5 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.