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NCT03679650 · ClinicalTrials.gov registry record · Phase 1
Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients
A Phase 1 study of Acute Myelogenous Leukemia, sponsored by Beth Israel Deaconess Medical Center.
- Active
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
- 2
- Study locations
NCT03679650: Active Phase 1 study of Acute Myelogenous Leukemia, sponsored by Beth Israel Deaconess Medical Center.
NCT03679650 is a Phase 1 study of Acute Myelogenous Leukemia that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 28 participants, below the 139-participant average among 38 other Acute Myelogenous Leukemia trials with a reported enrollment target (80% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03679650, a Phase 1 study of Acute Myelogenous Leukemia, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
- 2
- Study locations
Study Summary
This research study is studying a cancer vaccine called Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) as a possible treatment for Acute Myelogenous Leukemia (AML). The interventions involved in this study are: * Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) * Decitabine, a chemotherapy drug
Primary Outcome
The fold-increase in AML specific T cells in the peripheral blood and bone marrow
Conditions Studied
Interventions
- BIOLOGICAL DC/AML fusion cells
Study Locations (2)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
- Dana Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2018-10-11 |
| Est. Completion | 2026-08-31 |
| Phase | Phase 1 |
What the registry record for NCT03679650 still lists
NCT03679650 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 139-participant average among 38 other Acute Myelogenous Leukemia trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Acute Myelogenous Leukemia appearing as the primary indexed condition, and to 1 intervention - of which DC/AML fusion cells is the first listed.
NCT03679650 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03679650 about?
NCT03679650 is a clinical study titled "Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in AML Patients". This research study is studying a cancer vaccine called Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) as a possible treatment for Acute Myelogenous Leukemia (AML). The interventions involved in this study are: * Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) * Decitabine, a chemotherapy d...
What is the current status of trial NCT03679650?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2018-10-11. Estimated completion is 2026-08-31.
What conditions does trial NCT03679650 study?
This clinical trial studies the following conditions: Acute Myelogenous Leukemia.
What interventions are being tested in trial NCT03679650?
The interventions under investigation include: DC/AML fusion cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT03679650?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03679650 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Myelogenous Leukemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03679650's enrollment target sits among peer trials
28 32nd of 38 higher than 7 of 38 other Acute Myelogenous Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Myelogenous Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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