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RECRUITING Phase 1

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

NCT06656494 · View on ClinicalTrials.gov ↗

Study Summary

Evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ICP-248 in combination with azacitidine in patients with acute myelogenous leukemia and Myelodysplastic Syndromes.

Interventions

  • DRUG Azacitidine
  • DRUG ICP-248

Study Locations (15)

Guangdong

  • Guangdong Provincial People's Hospital — Guangzhou
  • Nanfang Hospital Southern Medical University — Guangzhou

New York

  • NYU Langone Health — New York

Anhui

  • Anhui Provincial Hospita — Hefei

Beijing Municipality

  • Peking University People's Hospital — Beijing

Chongqing Municipality

  • The First Affiliated Hospital of Chongqing Medical University — Chongqing

Henan

  • Henan Cancer Hospital — Zhengzhou

Hubei

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology — Wuhan

Jiangsu

  • The First Affiliated Hospital of Soochow University — Suzhou

Trial Details

FieldValue
Enrollment Target 266 participants
Start Date 2024-12-18
Est. Completion 2028-01
Phase Phase 1

Sponsor

Beijing InnoCare Pharma Tech Co.

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06656494

The ClinicalTrials.gov registry entry for NCT06656494 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 266 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beijing InnoCare Pharma Tech Co., which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Acute Myelogenous Leukemia appearing as the primary indexed condition, and to 2 interventions — of which Azacitidine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06656494 reports 15 study locations spanning 14 distinct geographic areas — top geographies include Guangdong, New York, Anhui. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06656494 about?

NCT06656494 is a clinical study titled "ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies". Evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ICP-248 in combination with azacitidine in patients with acute myelogenous leukemia and Myelodysplastic Syndromes.

What is the current status of trial NCT06656494?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 266 participants. The study started on 2024-12-18. Estimated completion is 2028-01.

What conditions does trial NCT06656494 study?

This clinical trial studies the following conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndromes (MDS). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06656494?

The interventions under investigation include: Azacitidine (DRUG), ICP-248 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06656494?

This trial is sponsored by Beijing InnoCare Pharma Tech Co., which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06656494 being conducted?

This trial has 15 study locations across New York, Anhui, Beijing Municipality, Chongqing Municipality, Guangdong. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial