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Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
NCT02665065 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to demonstrate the efficacy of Iomab-B, in conjunction with a Reduced Intensity Conditioning (RIC) regimen and protocol-specified allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid Leukemia (AML).
Conditions Studied
Interventions
- DRUG Iomab-B
- DRUG Conventional Care
- PROCEDURE HCT
Study Locations (20)
New York
- Roswell Park Cancer Institute — Buffalo
- Weill Cornell Medicine — New York
- Memorial Sloan Kettering Cancer Center — New York
- Stony Brook University — Stony Brook
Ohio
- University Hospital of Cleveland Seidman Cancer Center — Cleveland
- The Ohio State University Comprehensive Cancer Center — Columbus
Texas
- Baylor Charles A. Sammons Cancer Center — Dallas
- MD Anderson Cancer Center — Houston
Arizona
- Banner MD Anderson Cancer Center — Gilbert
Connecticut
- Yale Cancer Center — New Haven
District of Columbia
- Georgetown University Medical Center — Washington D.C.
Florida
- Mayo Clinic — Jacksonville
Illinois
- Loyola University Medical Center — Maywood
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 153 participants |
| Start Date | 2016-06 |
| Est. Completion | 2026-12 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02665065
The ClinicalTrials.gov registry entry for NCT02665065 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 153 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Actinium Pharmaceuticals, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 9 conditions, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 3 interventions — of which Iomab-B is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02665065 reports 20 study locations spanning 15 distinct geographic areas — top geographies include New York, Ohio, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02665065 about?
NCT02665065 is a clinical study titled "Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia". The primary objective of this study is to demonstrate the efficacy of Iomab-B, in conjunction with a Reduced Intensity Conditioning (RIC) regimen and protocol-specified allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute...
What is the current status of trial NCT02665065?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 153 participants. The study started on 2016-06. Estimated completion is 2026-12.
What conditions does trial NCT02665065 study?
This clinical trial studies the following conditions: Acute Myeloid Leukemia, Acute Myelogenous Leukemia, Leukemia, Myeloid, Acute, AML, Bone Marrow Transplant. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02665065?
The interventions under investigation include: Iomab-B (DRUG), Conventional Care (DRUG), HCT (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02665065?
This trial is sponsored by Actinium Pharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02665065 being conducted?
This trial has 20 study locations across Arizona, Connecticut, District of Columbia, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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