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NCT04427709 · ClinicalTrials.gov registry record · Phase 2

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

A Phase 2 study of Chronic Pain and Osteoarthritis, Knee, sponsored by Wake Forest University Health Sciences.

Recruiting
Registry status
Phase 2
Development phase
38
Enrollment target
1
Study location

NCT04427709 is a Phase 2 study of Chronic Pain and Osteoarthritis, Knee that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 38 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04427709, a Phase 2 study of Chronic Pain and Osteoarthritis, Knee, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.

RECRUITING
Registry status
Phase 2
Development phase
38 participants
Enrollment target
1
Study location

Study Summary

The purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system. The parasympathetic nervous system is the part of the involuntary nervous system that is sometimes called the "rest and digest" system; the parasympathetic system conserves energy as it slightly slows the heart rate, increases intestinal and gland activity, and relaxes sphincter muscles in the gastrointestinal tract.

Conditions Studied

Chronic Pain Osteoarthritis, Knee

Interventions

  • DRUG Placebo
  • DRUG Oxytocin

Study Locations (1)

North Carolina

  • Wake Forest Baptist Health - Winston-Salem

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2020-11-30
Est. Completion 2026-12
Phase Phase 2

Sponsor

Wake Forest University Health Sciences

1,140 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04427709

The ClinicalTrials.gov registry entry for NCT04427709 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (95% lower). The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04427709 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT04427709 about?

NCT04427709 is a clinical study titled "Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity". The purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system. The parasympathetic nervous system is the part of the involuntary nervous system that is sometimes ...

What is the current status of trial NCT04427709?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 38 participants. The study started on 2020-11-30. Estimated completion is 2026-12.

What conditions does trial NCT04427709 study?

This clinical trial studies the following conditions: Chronic Pain, Osteoarthritis, Knee.

What interventions are being tested in trial NCT04427709?

The interventions under investigation include: Placebo (DRUG), Oxytocin (DRUG).

Who is sponsoring clinical trial NCT04427709?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04427709 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.