Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 9 of 30

COMPLETED NA

Influence of Stress on Encoding and Prediction

NCT05920161

TERMINATED Early Phase 1

Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis

NCT05664763

COMPLETED NA

Single-Session Web-Based Training in Self-Compassion

NCT05715034

TERMINATED Phase 1

Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases

NCT05408871

COMPLETED NA

Dissemination and Implementation of Improving Pediatric Obesity Practice Using Prompts

NCT05627011

COMPLETED NA

Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes

NCT05706701

COMPLETED NA

Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)

NCT05770947

COMPLETED NA

Cognitive Training in Parkinson's Disease

NCT05495997

COMPLETED NA

Blood Pressure Monitoring in Hypertensive Populations: Device Testing, Feasibility, Acceptability

NCT05601414

COMPLETED NA

A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse

NCT05517382

COMPLETED Phase 1

Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products

NCT04226690

COMPLETED Phase 1

Effects of E-cigarette Flavors on Youth TCORS 2.0

NCT03634839

COMPLETED Phase 2

Varenicline for Treatment of E-cigarette Dependence

NCT05541497

COMPLETED NA

Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use

NCT05325788

TERMINATED NA

WithDRawal Impact Of Postoperative Beta-Blocker

NCT05414331

COMPLETED NA

QBSafe: a Randomized Trial of a Novel Intervention to Improve Care for People Living With Type 2 Diabetes.

NCT05553912

COMPLETED Phase 2

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes

NCT04038515

COMPLETED

Defining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement (DEFINE-TAVR) Study.

NCT05567809

COMPLETED NA

A Multi-level Intervention to Increase Access and Use of the Patient Portal

NCT05180721

COMPLETED NA

Electronic Health Record Strategies to Promote Diverse Participation in Research

NCT05348603

COMPLETED Phase 1

Topical Antibacterial Agents for Prevention of COVID-19

NCT05449392

COMPLETED Phase 1

Standardized Field Test for Marijuana Impairment II

NCT05115513

COMPLETED Phase 1

Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy

NCT05374564

COMPLETED NA

Water Content in E-Liquids

NCT05257109

COMPLETED NA

Patient Navigator Intervention for Diabetic Retinopathy

NCT05188703

COMPLETED NA

Computer Based Treatment for Cognitive Behavioral Therapy and Cooperative Pain Education and Self-Management

NCT05204576

COMPLETED NA

Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic Pain

NCT05370326

COMPLETED NA

Postpartum Video Education

NCT05159726

COMPLETED NA

Reducing Eco-anxiety Using Selfies

NCT05372705

COMPLETED Early Phase 1

Sex Differences in Neural Response to Cannabidiol

NCT04777643

COMPLETED NA

Myoelectric Activity Following Colorectal Surgery and Return of Bowel Function

NCT05298774

COMPLETED NA

Implementing and Evaluating a Social-Emotional Learning Program for Refugee Children During the COVID-19 Pandemic

NCT04931888

COMPLETED Phase 1

Effects of Menthol in E-cigarettes on Smoking Behaviors

NCT04521647

COMPLETED

Novel Real-world Methods in Social Drinkers and AUD

NCT05155176

TERMINATED NA

Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm

NCT05214131

COMPLETED NA

Patient Self Measurement of Post-Void Residual Bladder Volume (PVR) Using Ultrasound

NCT05295823

COMPLETED Phase 1

Novel in Vivo Synaptic Imaging in Experienced Meditators

NCT05418608

COMPLETED NA

Mindfulness Based Therapy for Insomnia in Black Women

NCT04951466

COMPLETED

Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function

NCT04419831

COMPLETED

The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study

NCT05294705

COMPLETED NA

Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms

NCT05317481

COMPLETED Phase 3

Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis

NCT04173169

COMPLETED NA

Community Partnership for Healthy Sleep: Sleep Well, Bee Well Part 2

NCT05130229

COMPLETED NA

Reducing Transphobia Among Adolescents Through a Brief Video Intervention

NCT04969003

COMPLETED Phase 2

Effect of Endotoxin on Alcohol Consumption

NCT04527185

COMPLETED NA

A PPG Sensor-Based Feedback Intervention for Heavy Drinking Young Adults

NCT05090995

COMPLETED Phase 1

Nicotine Differences in Smokers

NCT05159934

COMPLETED NA

Compassion Training and Mindfulness Training for Social Well-Being and Mental Health

NCT05227794

COMPLETED NA

A Pilot Study of Evidence-based Guided Self-help for the Treatment of Binge Eating

NCT05143866

TERMINATED Phase 4

Ocrelizumab for Preventing Clinical Multiple Sclerosis in Individuals With Radiologically Isolated Disease.

NCT04877457

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Yale University pipeline card: 1,492 registered trials from official public datasets.Report a data error.