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NCT05418608 · ClinicalTrials.gov registry record · Phase 1
Novel in Vivo Synaptic Imaging in Experienced Meditators
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT05418608: Completed Phase 1 study, sponsored by Yale University.
NCT05418608 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05418608, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
To utilize positron emission tomography (PET) imaging to characterize the distribution of (aka \[11C\]APP311at the Yale PET Center) in cortical and subcortical areas in experienced meditators compared to non-meditating controls.
Primary Outcome
Imaging data was analyzed using kinetic modeling approaches to quantitate total tracer binding, volume of distribution, and binding potential, specifically voxel-by-voxel compartment model fitting with the arterial input function. Positron emission tomography (PET) images will be registered to the subject's T1-weighted magnetic resonance (MR) images, and then registered to an magnetic resonance template. Gray matter regions of interest are determined by combining a predefined set of regions, def
Interventions
- DRUG Radiotracer
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2022-04-21 |
| Est. Completion | 2024-04-01 |
| Phase | Phase 1 |
What the finished NCT05418608 record still lists
NCT05418608 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 1 intervention - of which Radiotracer is the first listed.
NCT05418608 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05418608 about?
NCT05418608 is a clinical study titled "Novel in Vivo Synaptic Imaging in Experienced Meditators". To utilize positron emission tomography (PET) imaging to characterize the distribution of (aka \[11C\]APP311at the Yale PET Center) in cortical and subcortical areas in experienced meditators compared to non-meditating controls.
What is the current status of trial NCT05418608?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2022-04-21. Estimated completion is 2024-04-01.
What interventions are being tested in trial NCT05418608?
The interventions under investigation include: Radiotracer (DRUG).
Who is sponsoring clinical trial NCT05418608?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05418608's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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