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NCT05706701 · ClinicalTrials.gov registry record · NA

Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes

A NA study of Nicotine Vaping, sponsored by Yale University.

Completed
Registry status
NA
Development phase
36
Enrollment target
1
Study location

NCT05706701 is a NA study of Nicotine Vaping that has completed, run by Yale University. The registered enrollment target is 36 participants, below the 343-participant average among 5 other Nicotine Vaping trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05706701, a NA study of Nicotine Vaping, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

The investigators will examine the relationship between nicotine flux, nicotine form, and the rate and dose of nicotine delivery. Participants will puff on electronic nicotine delivery system (ENDS) devices under conditions that differ by flux and form, while arterial blood is sampled in high time resolution. The outcome will indicate the degree to which nicotine flux and form determine the speed and dose of ENDS nicotine delivery, and thus, abuse liability.

Conditions Studied

Nicotine Vaping

Interventions

  • OTHER Nicotine vaping visit 1 (free-base nicotine)
  • OTHER Nicotine vaping visit 1 (protonated nicotine)
  • OTHER Nicotine vaping visit 2 (free-base nicotine)
  • OTHER Nicotine vaping visit 2 (protonated nicotine)

Study Locations (1)

Connecticut

  • Human Research Unit (HRU) - New Haven

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2023-02-01
Est. Completion 2024-05-17
Phase NA

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT05706701

The ClinicalTrials.gov registry entry for NCT05706701 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 343-participant average among 5 other Nicotine Vaping trials with a reported enrollment target (90% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Nicotine Vaping appearing as the primary indexed condition, and to 4 interventions - of which Nicotine vaping visit 1 (free-base nicotine) is the first listed.

NCT05706701 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT05706701 about?

NCT05706701 is a clinical study titled "Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes". The investigators will examine the relationship between nicotine flux, nicotine form, and the rate and dose of nicotine delivery. Participants will puff on electronic nicotine delivery system (ENDS) devices under conditions that differ by flux and form, while arterial blood is sampled in high time r...

What is the current status of trial NCT05706701?

This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2023-02-01. Estimated completion is 2024-05-17.

What conditions does trial NCT05706701 study?

This clinical trial studies the following conditions: Nicotine Vaping.

What interventions are being tested in trial NCT05706701?

The interventions under investigation include: Nicotine vaping visit 1 (free-base nicotine) (OTHER), Nicotine vaping visit 1 (protonated nicotine) (OTHER), Nicotine vaping visit 2 (free-base nicotine) (OTHER), Nicotine vaping visit 2 (protonated nicotine) (OTHER).

Who is sponsoring clinical trial NCT05706701?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05706701 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.