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NCT04521647 · ClinicalTrials.gov registry record · Phase 1
Effects of Menthol in E-cigarettes on Smoking Behaviors
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 14
- Enrollment target
NCT04521647: Completed Phase 1 study, sponsored by Yale University.
NCT04521647 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04521647, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
The overall goal of this proposal is to understand the relationship between nicotine metabolism and menthol flavor in e-cigarettes on smoking behavior in smokers.
Primary Outcome
Mean plasma levels obtained after e-cigarette administration at each lab session (lab 1 and lab 2).
Interventions
- DRUG Nicotine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2022-05-10 |
| Est. Completion | 2023-07-25 |
| Phase | Phase 1 |
What the finished NCT04521647 record still lists
NCT04521647 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 1 intervention - of which Nicotine is the first listed.
NCT04521647 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04521647 about?
NCT04521647 is a clinical study titled "Effects of Menthol in E-cigarettes on Smoking Behaviors". The overall goal of this proposal is to understand the relationship between nicotine metabolism and menthol flavor in e-cigarettes on smoking behavior in smokers.
What is the current status of trial NCT04521647?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2022-05-10. Estimated completion is 2023-07-25.
What interventions are being tested in trial NCT04521647?
The interventions under investigation include: Nicotine (DRUG).
Who is sponsoring clinical trial NCT04521647?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04521647's enrollment target sits among peer trials
14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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