Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 24 of 30

COMPLETED

Reproductive Medicine Network Biologic Specimen Repository

NCT01180387

COMPLETED Phase 2

Intra-arterial Y-90 TheraSpheres for Hepatic Metastases From Solid Tumors

NCT01177007

COMPLETED

Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion

NCT01137409

COMPLETED NA

Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.

NCT01194479

COMPLETED NA

Alcohol Pharmacotherapy for HIV+ Prisoners

NCT01077310

COMPLETED Phase 1

Benefits Management for People With Psychiatric Disabilities

NCT01329393

COMPLETED Phase 2

Study of Computer-Based Treatment for Drug Dependence

NCT01315184

COMPLETED NA

Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

NCT01240993

COMPLETED

Evaluating a New Echocardiography Imaging Procedure for Evaluating Heart Function

NCT00661323

COMPLETED

Neural Functioning of Feeding Centers in Obese Youth

NCT01808846

COMPLETED Phase 1

Incentive-based Intervention for Smoking Cessation and Prevention in High Schools

NCT01173835

COMPLETED Phase 2

N-acetylcysteine (NAC) for Children With Tourette Syndrome

NCT01172288

COMPLETED NA

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

NCT01259466

COMPLETED Phase 3

Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation

NCT01044862

COMPLETED

Tdap Vaccination for Infant Caregivers

NCT01233401

COMPLETED

Deceased Donor Biomarkers and Recipient Outcomes

NCT01848249

TERMINATED Phase 3

Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis

NCT00767338

COMPLETED Phase 2

Modafinil, Sleep Architecture and Cocaine Relapse

NCT01137396

COMPLETED

Continuous Glucose Monitoring in Critically Ill Surgical Patients

NCT01108640

COMPLETED Phase 1

Ketamine for Low Mood States in the ER

NCT01209845

COMPLETED Phase 1

Galantamine Effects on Nicotine Responses in Smokers

NCT01417429

COMPLETED Phase 3

The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes

NCT01010386

COMPLETED NA

HIV Testing and Brief Alcohol Intervention for Young Drinkers in the Emergency Department

NCT01573065

COMPLETED Early Phase 1

The Effects of Cannabidiol and ∆-9-THC in Humans

NCT01180374

COMPLETED NA

A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia

NCT01232790

COMPLETED NA

Regulation of Arginine-vasopressin (AVP)

NCT02626832

COMPLETED NA

Single Daily Dosage of Trientine for Maintenance Treatment for Wilson Disease

NCT01472874

COMPLETED NA

Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children

NCT01050387

COMPLETED Phase 2

Abstinence-Linked Money Management Multisite

NCT01327586

COMPLETED Phase 1

Dosing Study of Cranberry Capsules for the Prevention of Bacteriuria in Nursing Home Residents

NCT01033383

COMPLETED NA

Enhancing a High School Based Smoking Cessation Program

NCT01145001

TERMINATED Phase 3

Milestones of Adjustment Post-Psychosis

NCT01192594

COMPLETED Phase 2

N-Acetylcysteine for Pediatric Trichotillomania

NCT00993265

COMPLETED Phase 2

Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders

NCT01000987

COMPLETED Phase 3

A Trial to Reduce Pneumonia in Nursing Home Residents

NCT00975780

COMPLETED NA

Lifestyle Modification for Weight Loss in Schizophrenia

NCT00990925

COMPLETED Phase 1

A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma Patients

NCT01561833

COMPLETED Phase 2

Nicotine Vaccination and Nicotinic Receptor Occupancy

NCT00996034

COMPLETED NA

Minding the Baby Home Visiting: Program Evaluation

NCT01458145

COMPLETED Phase 3

An Intervention to Improve Outcomes in Patients With Advanced Cancer

NCT01272024

COMPLETED Phase 2

Reducing Obesity and Type 2 Diabetes in High Risk Youth

NCT01560676

COMPLETED NA

Prevention of Type 2 Diabetes in Children With a Family-based Healthy Lifestyle Program

NCT01030978

COMPLETED Phase 1

Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse

NCT00585780

COMPLETED Phase 1

Clinical Trial of Integrated Treatment for Pain and Opioid Dependence

NCT00634803

COMPLETED Phase 1

Galantamine Effects on Cognitive Function in Marijuana Users

NCT00969696

COMPLETED

Positron Emission Tomography (PET) Imaging of Pancreatic Beta-Cell Mass in Healthy and Type 1 Diabetic Patients

NCT00958997

COMPLETED NA

Cognitive Behavioral Therapy for Insomnia in Stable Heart Failure

NCT02827799

COMPLETED NA

The Development of a Domestic Violence Perpetrator Collusion Measurement Tool

NCT01942616

TERMINATED Early Phase 1

Smoking Cessation Treatment for Head and Neck Cancer Patients

NCT00931021

TERMINATED

A Study to Examine the Human Gastrointestinal Tract Using the Confocal Endomicroscope

NCT01262937

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.