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NCT01010386 · ClinicalTrials.gov registry record · Phase 3
The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes
A Phase 3 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 3
- Development phase
- 851
- Enrollment target
NCT01010386: Completed Phase 3 study, sponsored by Yale University.
NCT01010386 is a Phase 3 study that has completed, run by Yale University. The registered enrollment target is 851 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01010386, a Phase 3 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 851 participants
- Enrollment target
Study Summary
Primary Aim * Evaluate whether human embryo exposure to physiologic levels of oxygen during culture improves the percentage of women who deliver a baby following in vitro fertilization and embryo transfer. Hypothesis to be tested: Physiologic oxygen tension during embryo culture, which approximates the oxygen tension in the fallopian tube and uterus, improves live birth rate in clinical In Vitro Fertilization Embryo Transfer (IVF-ET). Secondary Aims Evaluate whether human embryo exposure to physiologic levels of oxygen during culture during in vitro fertilization and embryo transfer * improves embryo cleavage * improves clinical pregnancy rate * reduces multiple pregnancy rate * reduces miscarriage rate Hypothesis to be tested: Physiologic oxygen tension during embryo culture, which approximates the oxygen tension in the fallopian tube and uterus, improves embryo cleavage and clinical pregnancy rates and reduces miscarriage rates in clinical IVF-ET.
Interventions
- PROCEDURE Atmospheric oxygen tension
- PROCEDURE Physiologic oxygen tension
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 851 participants |
| Start Date | 2010-03 |
| Est. Completion | 2014-02 |
| Phase | Phase 3 |
What the finished NCT01010386 record still lists
NCT01010386 is an interventional study that assigns participants to a tested intervention. The registered 851 participants enrollment target is mid-sized for trials with a published cap, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (10% higher).
The record links to 0 conditions, and to 2 interventions - of which Atmospheric oxygen tension is the first listed.
NCT01010386 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01010386 about?
NCT01010386 is a clinical study titled "The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes". Primary Aim * Evaluate whether human embryo exposure to physiologic levels of oxygen during culture improves the percentage of women who deliver a baby following in vitro fertilization and embryo transfer. Hypothesis to be tested: Physiologic oxygen tension during embryo culture, which approximate...
What is the current status of trial NCT01010386?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 851 participants. The study started on 2010-03. Estimated completion is 2014-02.
What interventions are being tested in trial NCT01010386?
The interventions under investigation include: Atmospheric oxygen tension (PROCEDURE), Physiologic oxygen tension (PROCEDURE).
Who is sponsoring clinical trial NCT01010386?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01010386's enrollment target sits among peer trials
851 386th of 2000 higher than 1,614 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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