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NCT01137396 · ClinicalTrials.gov registry record · Phase 2
Modafinil, Sleep Architecture and Cocaine Relapse
A Phase 2 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 2
- Development phase
- 114
- Enrollment target
NCT01137396: Completed Phase 2 study, sponsored by Yale University.
NCT01137396 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 114 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01137396, a Phase 2 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 114 participants
- Enrollment target
Study Summary
The medication modafinil has been shown to reduce cocaine use in some cocaine users. The investigators have shown that modafinil taken in the morning improves sleep in chronic cocaine users. The investigators hypothesize that the beneficial effects of modafinil in reducing cocaine use may be related to specific effects modafinil has on sleep. This study will measure sleep and cocaine use in cocaine dependent persons who are trying to stop using cocaine, and will test the connection between modafinil's effects on sleep and cocaine use.
Interventions
- BEHAVIORAL Cognitive Behavioral Therapy
- DRUG Modafinil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2010-04 |
| Est. Completion | 2015-02 |
| Phase | Phase 2 |
What the finished NCT01137396 record still lists
NCT01137396 is an interventional study that assigns participants to a tested intervention. The registered 114 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (14% lower).
The record links to 0 conditions, and to 2 interventions - of which Cognitive Behavioral Therapy is the first listed.
NCT01137396 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01137396 about?
NCT01137396 is a clinical study titled "Modafinil, Sleep Architecture and Cocaine Relapse". The medication modafinil has been shown to reduce cocaine use in some cocaine users. The investigators have shown that modafinil taken in the morning improves sleep in chronic cocaine users. The investigators hypothesize that the beneficial effects of modafinil in reducing cocaine use may be related...
What is the current status of trial NCT01137396?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 114 participants. The study started on 2010-04. Estimated completion is 2015-02.
What interventions are being tested in trial NCT01137396?
The interventions under investigation include: Cognitive Behavioral Therapy (BEHAVIORAL), Modafinil (DRUG).
Who is sponsoring clinical trial NCT01137396?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01137396's enrollment target sits among peer trials
114 627th of 2000 higher than 1,370 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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