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NCT00958997 · ClinicalTrials.gov registry record
Positron Emission Tomography (PET) Imaging of Pancreatic Beta-Cell Mass in Healthy and Type 1 Diabetic Patients
A clinical trial, sponsored by Yale University.
- Completed
- Registry status
- 16
- Enrollment target
NCT00958997: Completed study, sponsored by Yale University.
NCT00958997 is a clinical trial that has completed, run by Yale University. The registered enrollment target is 16 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00958997 has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
Study Summary
Pancreatic Islet beta-cells are responsible for synthesizing and secreting appropriate amounts of insulin to regulate blood glucose levels. One factor in the development of diabetes is the loss of beta-cells. Developing treatments to prevent or restore islet beta-cell mass (BCM) in diabetic patients is hampered by a lack of methods for the non-invasive imaging of these cells. This study is designed to evaluate a radiolabeled compound that binds to the pancreatic islet. The investigators will test the ability of one promising imaging compound, 18F-9-fluoropropyl-(+)-dihydrotetrabenazine (18F-FP-DTBZ), to measure the amount of pancreatic islet beta-cells in patients with long-standing type-1 diabetes and in age-weight-matched healthy control subjects.
Interventions
- DRUG 18F-FP-DTBZ (18F-AV-133)
- BIOLOGICAL Arginine-hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2009-08 |
| Est. Completion | 2012-05 |
What the finished NCT00958997 record still lists
NCT00958997 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 16 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which 18F-FP-DTBZ (18F-AV-133) is the first listed.
NCT00958997 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00958997 about?
NCT00958997 is a clinical study titled "Positron Emission Tomography (PET) Imaging of Pancreatic Beta-Cell Mass in Healthy and Type 1 Diabetic Patients". Pancreatic Islet beta-cells are responsible for synthesizing and secreting appropriate amounts of insulin to regulate blood glucose levels. One factor in the development of diabetes is the loss of beta-cells. Developing treatments to prevent or restore islet beta-cell mass (BCM) in diabetic patients...
What is the current status of trial NCT00958997?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2009-08. Estimated completion is 2012-05.
What interventions are being tested in trial NCT00958997?
The interventions under investigation include: 18F-FP-DTBZ (18F-AV-133) (DRUG), Arginine-hydrochloride (BIOLOGICAL).
Who is sponsoring clinical trial NCT00958997?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
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