Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 16 of 30

COMPLETED

Objective Evaluation of Paclitaxel/Docetaxel-induced Neuropathy in Breast Cancer Patients

NCT03872141

COMPLETED NA

Skin Health in Young Adults - Preventing Indoor Tanning and Promoting Sun Protection

NCT03132012

COMPLETED Phase 4

Sugammadex and Decreased Time to Extubation

NCT03196167

COMPLETED Phase 2

Phase II Anetumab Ravtansine in Pre-treated Mesothelin-expressing Pancreatic Cancer

NCT03023722

COMPLETED Phase 2

Saracatinib and Alcohol Drinking

NCT02955186

COMPLETED NA

Yo Puedo! Diabetes Self-Management Education + mHealth in Mexico City

NCT03159299

COMPLETED Phase 1

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2

NCT03168191

COMPLETED Phase 1

Treatment Targets for Inflamed Intracranial Atherosclerosis on Vessel Wall MRI

NCT03084523

COMPLETED NA

Mindfulness - Based Stress Reduction and the Relationship on Inflammation in Autoimmune Hepatitis

NCT02950077

TERMINATED Phase 2

Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Trial

NCT03003390

COMPLETED Phase 2

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

NCT03093155

COMPLETED NA

Opioid Use Disorder in the Emergency Department: CTN 0069

NCT03023930

COMPLETED Phase 1

Imaging the Neuroimmune System in PTSD

NCT04236986

COMPLETED Phase 2

Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

NCT02979977

COMPLETED NA

Impact of Switching to Non-Menthol Cigarettes Among Smokers

NCT03075839

COMPLETED Phase 1

Fish Oil vs. Placebo on Subjective Effects of Alcohol

NCT03010917

COMPLETED Phase 1

New Approaches to Smoking Cessation in Heavy Drinkers

NCT02151591

COMPLETED

Pathogenesis of Youth Onset Type 2 Diabetes and Prediabetes

NCT03195400

COMPLETED Phase 2

Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Acute Treatment

NCT03045341

COMPLETED

Community Partnership for Healthy Sleep

NCT03045874

COMPLETED NA

Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders

NCT02742246

COMPLETED Phase 3

Optimizing Tobacco Dependence Treatment in the Emergency Department

NCT02896400

COMPLETED Phase 1

Harnessing the Power of Technology: MOMBA for Postpartum Smoking

NCT02237898

TERMINATED Phase 1

Pilot Study Of Anti-Programmed Death Ligand-1 (Anti-PD-L1, Atezolizumab) In Asymptomatic Myeloma

NCT02784483

COMPLETED NA

A Pilot Study of Biomarkers of Stress in Youth Who Use Teens.Connect

NCT02970656

COMPLETED NA

Pivotal Response Treatment (PRT) Telemedicine

NCT03045263

COMPLETED Early Phase 1

Optimizing Acquisition Parameters and Interpretive Methods of FDG-PET/CT With Rb-82

NCT03048097

COMPLETED NA

Novel Device for Rapid Fluid Administration

NCT03074682

COMPLETED Phase 2

Efficacy of a Therapeutic Combination of Dronabinol and PEA for Tourette Syndrome

NCT03066193

COMPLETED

Comparative Effectiveness of Sentinel Lymph Node Biopsy for Ductal Carcinoma In Situ

NCT02908178

COMPLETED Early Phase 1

The Effect of Nicotine Delivery Rate on Reinforcement

NCT03134339

COMPLETED Early Phase 1

Nicotine Reinforcement and Aversion in Young Adult Light Smokers

NCT01495819

COMPLETED NA

Evaluation of the Implementation and Effectiveness of IPP-HPV

NCT02994290

COMPLETED NA

Cognitive Therapy to Sustain the Antidepressant Effects of Intravenous Ketamine in Treatment-resistant Depression

NCT03027362

COMPLETED NA

Development of a Videogame Prototype Targeting Cigarette and Marijuana Smoking, and Tobacco Product Prevention Among Young Adolescents

NCT03107936

COMPLETED Phase 2

Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder

NCT03017508

COMPLETED NA

Cognitive Remediation Therapy (CRT) for Adults Treated for Cancer

NCT03285048

COMPLETED

Aggressive Incidents in Medical Settings Study

NCT03041272

COMPLETED Phase 1

Psilocybin for the Treatment of Cluster Headache

NCT02981173

COMPLETED

The Neural Correlates of Cannabis Use

NCT03104257

COMPLETED NA

Computer Based Training in CBT in Primary Care

NCT03013478

COMPLETED Phase 1

TAS-OX for Refractory Metastatic Colon Cancer

NCT02848079

COMPLETED

Autism Biomarker Consortium for Clinical Trials

NCT02996669

COMPLETED Phase 1

Neuroscience of Marijuana Impaired Driving

NCT02757313

TERMINATED NA

Glycemic Index of Commonly Consumed Sweeteners

NCT02931578

COMPLETED Phase 1

Neuroendocrine Response to Oral Alcohol Administration

NCT03165942

TERMINATED Phase 2

Pembrolizumab in HNSCC With Residual Disease After Radiation

NCT02892201

COMPLETED Phase 2

Progesterone Effect on Individuals Diagnoses With AD and PTSD.

NCT02187224

COMPLETED NA

A Reinforcement Approach to Increase Use of CGM

NCT02907346

COMPLETED Phase 2

Pembrolizumab in Ultramutated and Hypermutated Endometrial Cancer

NCT02899793

← Previous Page 16 of 30 Next →

Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.