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NCT02725619 · ClinicalTrials.gov registry record · NA

CBT for Anxiety in Children With Autism

A NA study, sponsored by Yale University.

Completed
Registry status
NA
Development phase
70
Enrollment target

NCT02725619: Completed NA study, sponsored by Yale University.

NCT02725619 is a NA study that has completed, run by Yale University. The registered enrollment target is 70 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02725619, a NA study, has completed, sponsored by Yale University.

COMPLETED
Registry status
NA
Development phase
70 participants
Enrollment target

Study Summary

This is a randomized controlled trial of Cognitive Behavioral Therapy (CBT) versus Psychoeducation and Supportive Therapy (PST) in children with Autism Spectrum Disorder and moderate to severe anxiety. The study will utilize fMRI to identify CBT-invoked changes in levels of activity/functional connectivity within the neural circuits involved in emotion regulation and social perception. Matched typically developing children without autism and/or anxiety will be scanned twice, 16 weeks apart, to enable interpretation of treatment-evoked change relative to normative development.

Primary Outcome

The PARS is a 50-item semi-structures interview of anxiety that will be conducted by an expert clinician. Endorsed symptoms are rated using 0-5 severity scale on 7 dimensions and a sum of scores for 5 of 7 dimensions constitute the total PARS score.

Interventions

  • BEHAVIORAL CBT
  • BEHAVIORAL PST

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2016-04
Est. Completion 2022-10-12
Phase NA
Yale University

1,492 total trials

What the finished NCT02725619 record still lists

NCT02725619 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which CBT is the first listed.

NCT02725619 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02725619 about?

NCT02725619 is a clinical study titled "CBT for Anxiety in Children With Autism". This is a randomized controlled trial of Cognitive Behavioral Therapy (CBT) versus Psychoeducation and Supportive Therapy (PST) in children with Autism Spectrum Disorder and moderate to severe anxiety. The study will utilize fMRI to identify CBT-invoked changes in levels of activity/functional conne...

What is the current status of trial NCT02725619?

This trial is currently completed. It is a NA study. The enrollment target is 70 participants. The study started on 2016-04. Estimated completion is 2022-10-12.

What interventions are being tested in trial NCT02725619?

The interventions under investigation include: CBT (BEHAVIORAL), PST (BEHAVIORAL).

Who is sponsoring clinical trial NCT02725619?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02725619's enrollment target sits among peer trials

70 1103rd of 2000 higher than 868 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02725619, the US trial registry maintained by the National Library of Medicine. NCT02725619 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.