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NCT02994875 · ClinicalTrials.gov registry record · Early Phase 1

Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence

A Early Phase 1 study, sponsored by Yale University.

Completed
Registry status
Early Phase 1
Development phase
21
Enrollment target

NCT02994875: Completed Early Phase 1 study, sponsored by Yale University.

NCT02994875 is a Early Phase 1 study that has completed, run by Yale University. The registered enrollment target is 21 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02994875, a Early Phase 1 study, has completed, sponsored by Yale University.

COMPLETED
Registry status
Early Phase 1
Development phase
21 participants
Enrollment target

Study Summary

The objective of this research is to identify the functional neural mechanisms (as assessed using fMRI) of short-term N-acetylcysteine (NAC) administration among methadone-maintained individuals with cocaine dependence.

Primary Outcome

The primary outcome measure for this study is change (NAC versus placebo) in neural network engagement during fMRI task performance.

Interventions

  • OTHER Placebo
  • DIETARY_SUPPLEMENT N-acetylcysteine

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2016-05
Est. Completion 2020-09
Phase Early Phase 1
Yale University

1,492 total trials

What the finished NCT02994875 record still lists

NCT02994875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02994875 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02994875 about?

NCT02994875 is a clinical study titled "Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence". The objective of this research is to identify the functional neural mechanisms (as assessed using fMRI) of short-term N-acetylcysteine (NAC) administration among methadone-maintained individuals with cocaine dependence.

What is the current status of trial NCT02994875?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 21 participants. The study started on 2016-05. Estimated completion is 2020-09.

What interventions are being tested in trial NCT02994875?

The interventions under investigation include: Placebo (OTHER), N-acetylcysteine (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02994875?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02994875's enrollment target sits among peer trials

21 1130th of 2000 higher than 845 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02994875, the US trial registry maintained by the National Library of Medicine. NCT02994875 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.