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NCT07228429 · ClinicalTrials.gov registry record
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
A clinical trial of Systemic Sclerosis (SSc) and Calcinosis Cutis, sponsored by Yale University.
- Recruiting
- Registry status
- 56
- Enrollment target
- 1
- Study location
NCT07228429: Recruiting study of Systemic Sclerosis (SSc) and Calcinosis Cutis, sponsored by Yale University.
NCT07228429 is a study of Systemic Sclerosis (SSc) and Calcinosis Cutis that is actively recruiting participants, run by Yale University. The registered enrollment target is 56 participants, below the 95-participant average among 8 other Systemic Sclerosis (SSc) trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07228429, a study of Systemic Sclerosis (SSc) and Calcinosis Cutis, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response in clinical practice. The goal is to test the performance of the software.
Primary Outcome
An 18-question survey with an overall score of 0-10; each individual question ranges from 0-10, scores are totaled and averaged to and divided by 18 to create the overall score. Higher scores indicate higher disability from calcinosis.
Conditions Studied
Interventions
- DRUG Sodium Thiosulfate (STS)
- DRUG Sodium Thiosulfate Injection
Study Locations (1)
Connecticut
- Yale Scleroderma Program - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2025-10-14 |
| Est. Completion | 2026-07 |
What NCT07228429 shows while recruiting
NCT07228429 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 95-participant average among 8 other Systemic Sclerosis (SSc) trials with a reported enrollment target (41% lower).
The record links to 2 conditions, with Systemic Sclerosis (SSc) appearing as the primary indexed condition, and to 2 interventions - of which Sodium Thiosulfate (STS) is the first listed.
NCT07228429 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT07228429 about?
NCT07228429 is a clinical study titled "Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images". The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments, and potentially be used to assess disease course and treatment response i...
What is the current status of trial NCT07228429?
This trial is currently recruiting. The enrollment target is 56 participants. The study started on 2025-10-14. Estimated completion is 2026-07.
What conditions does trial NCT07228429 study?
This clinical trial studies the following conditions: Systemic Sclerosis (SSc), Calcinosis Cutis.
What interventions are being tested in trial NCT07228429?
The interventions under investigation include: Sodium Thiosulfate (STS) (DRUG), Sodium Thiosulfate Injection (DRUG).
Who is sponsoring clinical trial NCT07228429?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07228429 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Systemic Sclerosis (SSc)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07228429's enrollment target sits among peer trials
56 7th of 8 higher than 2 of 8 other Systemic Sclerosis (SSc) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Systemic Sclerosis (SSc) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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