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NCT06492252 · ClinicalTrials.gov registry record · NA
Speech Motor Learning and Retention (Aim 3)
A NA study, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT06492252: Recruiting NA study, sponsored by Yale University.
NCT06492252 is a NA study that is actively recruiting participants, run by Yale University. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06492252, a NA study, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well. The strategy for the proposed research is to identify individual brain areas that contribute causally to retention by disrupting their activity with transcranial magnetic stimulation (TMS). Investigators will also use functional magnetic resonance imaging (fMRI) which will enable identification of circuit-level activity which predicts either learning or retention of new movements, and hence test the specific contributions of candidate sensory and motor zones. In other studies, investigators will record sensory and motor evoked potentials over the course of learning to determine the temporal order in which individual sensory and cortical motor regions contribute. The goal here is to identify brain areas in which learning-related plasticity occurs first and which among these areas predict subsequent learning.
Primary Outcome
Audapter software will be used to alter the first and second formant frequencies of the spoken words and this is played back to subjects through headphones. Subjects will be tested both with unaltered feedback and with abruptly introduced frequency shifts.The change in the first (F1) and second format frequency (F2) values will be assessed using Praat.
Interventions
- DEVICE fMRI
- BEHAVIORAL Adaptation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-05-04 |
| Est. Completion | 2029-05-31 |
| Phase | NA |
What NCT06492252 shows while recruiting
NCT06492252 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which fMRI is the first listed.
NCT06492252 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06492252 about?
NCT06492252 is a clinical study titled "Speech Motor Learning and Retention (Aim 3)". The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well. The strategy for the proposed research is ...
What is the current status of trial NCT06492252?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2026-05-04. Estimated completion is 2029-05-31.
What interventions are being tested in trial NCT06492252?
The interventions under investigation include: fMRI (DEVICE), Adaptation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06492252?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06492252's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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