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NCT07457736 · ClinicalTrials.gov registry record · Early Phase 1
Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1
A Early Phase 1 study of Healthy Adult Participants, sponsored by Yale University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT07457736 is a Early Phase 1 study of Healthy Adult Participants that is actively recruiting participants, run by Yale University. The registered enrollment target is 32 participants, below the 72-participant average among 4 other Healthy Adult Participants trials with a reported enrollment target (56% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07457736, a Early Phase 1 study of Healthy Adult Participants, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
Evaluate \[18F\]GATT-44 (aka \[18F\]GAT44), to characterize its pharmacokinetic, metabolic, and in vivo binding profile, and assess the reproducibility of kinetic and binding parameters. Assess specific binding levels of \[18F\]GATT-44 by conducting a test-block study in humans. Estimate human dosimetry of \[18F\]GATT-44 by performing whole-body imaging studies.
Conditions Studied
Interventions
- DRUG [ 18F]GATT-44
Study Locations (1)
Connecticut
- Yale University PET Center - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2026-03 |
| Est. Completion | 2030-01 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07457736
The ClinicalTrials.gov registry entry for NCT07457736 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 72-participant average among 4 other Healthy Adult Participants trials with a reported enrollment target (56% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy Adult Participants appearing as the primary indexed condition, and to 1 intervention - of which [ 18F]GATT-44 is the first listed.
NCT07457736 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT07457736 about?
NCT07457736 is a clinical study titled "Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1". Evaluate \[18F\]GATT-44 (aka \[18F\]GAT44), to characterize its pharmacokinetic, metabolic, and in vivo binding profile, and assess the reproducibility of kinetic and binding parameters. Assess specific binding levels of \[18F\]GATT-44 by conducting a test-block study in humans. Estimate human dosim...
What is the current status of trial NCT07457736?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 32 participants. The study started on 2026-03. Estimated completion is 2030-01.
What conditions does trial NCT07457736 study?
This clinical trial studies the following conditions: Healthy Adult Participants.
What interventions are being tested in trial NCT07457736?
The interventions under investigation include: [ 18F]GATT-44 (DRUG).
Who is sponsoring clinical trial NCT07457736?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07457736 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
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