VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 34 of 34

COMPLETED Phase 4

Antiarrhythmic Effects of Spironolactone in Patients With ICDs

NCT04495712

COMPLETED NA

Cognitive Rehabilitation in Schizophrenia

NCT00248794

COMPLETED

Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

NCT00579410

COMPLETED NA

Shoe Modification and Knee Osteoarthritis

NCT00105365

COMPLETED

Genetic Research in Schizophrenia Using DNA Markers and Clinical Phenotypes

NCT00108303

COMPLETED Phase 3

Divalproex Sodium in the Treatment of PTSD (Post-Traumatic Stress Disorder)

NCT00108576

COMPLETED Phase 2

Testosterone Replacement Therapy in Chronic Spinal Cord Injury

NCT00266864

COMPLETED Phase 4

Humoral Determinants of Immunity to Pneumococcal Infection

NCT00304382

COMPLETED Phase 4

Standard Open Surgery Versus Endovascular Repair of Abdominal Aortic Aneurysm (AAA)

NCT00094575

COMPLETED

Relatively Healthy Male Veterans Observed Over Time to See What Types of Diseases Develop

NCT00076141

COMPLETED Phase 3

Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)

NCT00032487

COMPLETED Phase 2

Work Activity Augmented by Cognitive Rehabilitation for Schizophrenia

NCT00430560

COMPLETED

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

NCT00690755

COMPLETED

Post-Traumatic Stress Disorder (PTSD) Symptom Study

NCT00018798

COMPLETED Phase 2

Integrated Intervention for Substance Abusers With Depressive Disorders

NCT00018655

COMPLETED

Neural Networks and Language Recovery in Aphasia From Stroke: fMRI Studies

NCT00467103

COMPLETED Phase 3

Prostate Cancer Intervention Versus Observation Trial (PIVOT)

NCT00007644

COMPLETED Phase 3

The VA HDL Intervention Trial (HIT): Secondary Prevention of Coronary Heart Disease in Men With Low HDL-Cholesterol and Desirable LDL-Cholesterol

NCT00283335

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.