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NCT00248794 · ClinicalTrials.gov registry record · NA
Cognitive Rehabilitation in Schizophrenia
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 59
- Enrollment target
NCT00248794: Completed NA study, sponsored by VA Office of Research and Development.
NCT00248794 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 59 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00248794, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 59 participants
- Enrollment target
Study Summary
The study will investigate the viability of two cognitive rehabilitation strategies to improve functional outcomes for people with schizophrenia. Many people with schizophrenia experience impairments in cognitive function which limit their abilities. These impairments have been shown to precede the onset of illness and represent a vulnerability factor which is exacerbated by emerging psychotic symptoms. These impairments affect a range of functional domains including symptom severity, work function, symptom management, treatment, and overall quality of life. Recognizing the link between cognitive impairment and function, a few clinicals and researchers have attempted to remediate cognitive impairments by providing cognitive retraining programs similar to those used in traumatic brain injured patients or adaptive skills training. Cognitive retraining involves repetitive exercises to increase elemental cognitive functions including memory, attention, psychomotor speed, planning, and cognitive flexibility. Adaptive skill training involves didactic group exercises in social skills, activities of daily living, and symptom management. Each approach has demonstrated some rehabilitation benefits. This study will investigate the effectiveness of a combination of these two approaches on outcomes in schizophrenia.
Primary Outcome
This is a measure of cognitive flexibility and the ability to shift set in the face of a changing reinforcement. The measure reflects "density" of perseverative errors in relation to the overall test performance. It is computed by calculating the ration of perseverative errors to trials administered and multiplied by 100. Then the percentage score is translate using the available Standard Score Tables provided in the manual and converted to a standard score with a mean of 100, a maximum of 145 a
Interventions
- BEHAVIORAL Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG)
- BEHAVIORAL Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG)
- BEHAVIORAL Skills Group (SDG)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2004-06 |
| Est. Completion | 2009-10 |
| Phase | NA |
What the finished NCT00248794 record still lists
NCT00248794 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 3 interventions - of which Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG) is the first listed.
NCT00248794 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00248794 about?
NCT00248794 is a clinical study titled "Cognitive Rehabilitation in Schizophrenia". The study will investigate the viability of two cognitive rehabilitation strategies to improve functional outcomes for people with schizophrenia. Many people with schizophrenia experience impairments in cognitive function which limit their abilities. These impairments have been shown to precede the ...
What is the current status of trial NCT00248794?
This trial is currently completed. It is a NA study. The enrollment target is 59 participants. The study started on 2004-06. Estimated completion is 2009-10.
What interventions are being tested in trial NCT00248794?
The interventions under investigation include: Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG) (BEHAVIORAL), Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG) (BEHAVIORAL), Skills Group (SDG) (BEHAVIORAL).
Who is sponsoring clinical trial NCT00248794?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00248794's enrollment target sits among peer trials
59 1256th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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