VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 23 of 34

COMPLETED NA

Improving Weight Management at the VA

NCT02626819

COMPLETED NA

Blast Exposed Veterans With Auditory Complaints

NCT02122458

COMPLETED Early Phase 1

Remediation of Impaired Self-Regulation in Patients With Mild TBI

NCT02260570

COMPLETED NA

Staying Positive With Arthritis Study

NCT02223858

COMPLETED NA

Point-of-care Health Literacy and Activation Information to Improve Diabetes Care

NCT01876485

TERMINATED Phase 2

Lithium for Suicidal Behavior in Mood Disorders

NCT01928446

COMPLETED Early Phase 1

Premature Fatigue in Veterans With Heart Failure: Neuronal Influences

NCT02209610

TERMINATED Phase 2

Research Examining Gulf War Illness in Our Nations Service Members

NCT01846182

COMPLETED NA

RESCUE Stroke Caregiver Website to Enhance Discharge Planning

NCT01600131

COMPLETED NA

Building Employment Skills Through Therapy for Veterans

NCT01992913

COMPLETED NA

HRV Biofeedback in Pain Patients

NCT02426476

COMPLETED NA

Physical Activity and Participation

NCT02268916

COMPLETED NA

Improving Balance and Mobility

NCT02374463

COMPLETED NA

Veteran Peer-Assisted Computerized Cognitive Behavioral Therapy for Depression

NCT02057042

COMPLETED NA

Motor Training in PD

NCT02457832

COMPLETED NA

Effective Screening for Pain Study

NCT01816763

COMPLETED Phase 1

A Pilot Trial to Assess Low-Intensity Ultrasound in Osteoarthritis

NCT02034409

COMPLETED NA

Physical Activity for Older Adults Chronic Low Back Pain

NCT02327325

COMPLETED Phase 2

Fenofibrate Treatment in SCI

NCT02455336

COMPLETED Phase 2

Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI

NCT02458469

COMPLETED NA

Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD

NCT02391402

COMPLETED Phase 2

Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia

NCT02350127

COMPLETED NA

Evaluation of a Peer Coach-Led Intervention to Improve Pain Symptoms

NCT02380690

COMPLETED NA

Group Medical Visits in Heart Failure

NCT02481921

COMPLETED NA

Treatment Intensity - Apraxia of Speech

NCT02332915

COMPLETED NA

Optimizing Veteran-Centered Prostate Cancer Survivorship Care

NCT01900561

COMPLETED Phase 4

Computerized Cognitive Training for Diabetic Elderly Veterans

NCT01736124

COMPLETED Phase 2

Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression

NCT02360280

COMPLETED NA

Randomized Trial Comparison of Ototoxicity Monitoring Programs

NCT02099786

COMPLETED Phase 2

Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple Sclerosis

NCT02391961

COMPLETED NA

Effect of Heat Exposure on Cognition in Persons With Tetraplegia

NCT02488824

COMPLETED NA

Pilot Evaluation of AboutFace: Novel Peer Education Resource for Veterans

NCT02486692

COMPLETED Phase 3

Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase II

NCT02347098

COMPLETED NA

Improving Mood in Veterans in Primary Care

NCT02276807

COMPLETED NA

Mindfulness-Based Recovery in Veterans

NCT02326363

COMPLETED NA

Pilot Study to Improve Care Coordination

NCT02386189

COMPLETED NA

Evaluation of Methods for Implementation of a Comfort Care Order Set

NCT02383173

COMPLETED NA

Web-based Intervention to Reduce Alcohol Use in Veterans With Hepatitis C

NCT01707030

TERMINATED Phase 3

Effectiveness of Zonisamide in Alcohol Dependent Veterans

NCT02368431

COMPLETED NA

Relational Agent for Alcohol Screening and Treatment

NCT02030288

COMPLETED NA

Integrating Care After Exacerbation of COPD

NCT02021955

COMPLETED NA

Group CBT for Aggression in Veterans

NCT02233517

COMPLETED Phase 3

Lifestyle Intervention and Testosterone Replacement in Obese Seniors

NCT02367105

COMPLETED NA

Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)

NCT02248675

COMPLETED Phase 2

Cholinesterase Inhibitor Discontinuation

NCT02248636

COMPLETED NA

Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness

NCT01782378

COMPLETED NA

Race And CPAP Effectiveness

NCT01960465

COMPLETED NA

Developing Process-Specific Verbal Memory Interventions for Veterans With Tramatic Brain Injury (TBI)

NCT02310633

COMPLETED Phase 1

Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

NCT02461927

COMPLETED NA

Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT02929979

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.