University of Pittsburgh

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Pittsburgh sits in the top decile of US sponsors by registered trial count (#22 of 15,742 sponsors by registered trial count).

1,238 total trials 160 currently recruiting 917 completed early-phase tilt top decile by trial count

University of Pittsburgh: 1,238 sponsored US clinical trials, 160 recruiting.

University of Pittsburgh sponsors 1,238 registered US clinical trials on ClinicalTrials.gov, 160 of them currently recruiting, and 917 completed. 84 of these trials are in Phase 3-4 (later-stage) and 160 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 17 trials.

Top-decile sponsor footprint

University of Pittsburgh ranks in the top decile of sponsors by registered trial count (#22 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 66/100

917 of 1,014 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,238 total, page 25 of 25

COMPLETED Phase 4

Bupropion and Weight Control for Smoking Cessation - 1

NCT00006170

COMPLETED Phase 2

Improving Quality of Primary Care for Patients With Anxiety and/or Panic Disorders

NCT00102427

COMPLETED Phase 2

Treating Behavioral Disturbances in Individuals With Dementia

NCT00073658

COMPLETED

A Multi-Center Group to Study Acute Liver Failure in Children

NCT00986648

COMPLETED NA

Couples-Oriented Psychosocial Intervention for Osteoarthritis

NCT00230945

COMPLETED Phase 3

N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure

NCT00248625

COMPLETED Phase 4

Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals

NCT00178035

COMPLETED Phase 1

A Mentor-Based Approach to Long-Term Weight Loss

NCT00177697

COMPLETED

Antidepressant Use During Pregnancy

NCT00279370

COMPLETED Phase 2

Efficacy Trial of CDB 2914 for Emergency Contraception

NCT00271583

COMPLETED

Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease

NCT01039987

COMPLETED Phase 1

Dose-Response of Exercise on Long-Term Weight Loss

NCT00177762

COMPLETED Phase 3

Home Screening for Chlamydia Surveillance

NCT00177437

COMPLETED Phase 1

Calcitriol Plus Dexamethasone in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

NCT00010231

COMPLETED Phase 1

Gene Therapy in Treating Patients With Advanced Head and Neck Cancer

NCT00009841

COMPLETED Phase 4

Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression

NCT00178100

COMPLETED Phase 4

The Effects of Sleep Deprivation on Antidepressant Response

NCT00178074

COMPLETED

Genetic Linkage Study for Hereditary Pancreatitis

NCT00004475

COMPLETED Phase 1

Radiation Therapy in Treating Patients With Bile Duct, Gallbladder, or Pancreatic Cancer

NCT00003411

COMPLETED Phase 4

Paroxetine in the Treatment of Chronic Primary Insomnia

NCT00178048

TERMINATED Phase 2

LIFE-Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer

NCT00260598

COMPLETED Phase 1

Calcitriol Plus Paclitaxel in Treating Patients With Advanced Solid Tumors

NCT00009802

COMPLETED NA

Randomized Study of L-Baclofen in Patients With Refractory Trigeminal Neuralgia

NCT00004431

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Resected or Locally Advanced Unresectable Pancreatic Cancer

NCT00008099

COMPLETED Phase 1

Combination Chemotherapy With or Without Filgrastim in Treating Patients With Advanced Solid Tumors

NCT00008125

COMPLETED NA

Pathogenesis of Functional Hypothalamic Amenorrhea

NCT01674426

COMPLETED Phase 4

Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder

NCT00178061

COMPLETED NA

Coordinating Center for Enhancing ADRD Caregiving

NCT00178165

COMPLETED Phase 1

Octreotide and Doxorubicin in Treating Patients With Advanced Cancer

NCT00008073

COMPLETED Phase 1

Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors

NCT00008086

COMPLETED Phase 4

Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder

NCT00227968

COMPLETED NA

Maintenance Interpersonal Psychotherapy for Sustaining Remission of Depression

NCT00227981

COMPLETED Phase 3

Pharmacotherapy of Treatment-Resistant Mania

NCT00518947

COMPLETED Phase 4

Comparing Various Treatments for Achieving and Maintaining Remission of Depression

NCT00227955

COMPLETED

Central Venous Access Catheter Placement Using the Sonic Flashlight

NCT00330590

COMPLETED NA

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

NCT00002276

TERMINATED

Opioid Induced Loss of Local Anesthetic Potency in Patients Undergoing Total Knee Arthroplasty

NCT03294174

TERMINATED

Microbiologic Effect of Selective Decontamination of the Digestive Tract With Colistin, Gentamicin and Nystatin

NCT00250133

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Phase Distribution

PhaseTrial count
Phase 1 81
Phase 2 79
Phase 3 28
Phase 4 56

What is open in the University of Pittsburgh pipeline

160 recruiting of 1,238 indexed (13% open); 917 completed (74%).

Phase mix: 84 late (III/IV) vs 160 early (I/II) (early-phase heavy).

Top condition: Depression (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Pittsburgh: open-pipeline peers nationwide

Peers matched on 1,238 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 12%14%16%18%20%22% Total trials Recruiting share University of PittsburghNorthwestern UniversityEmory UniversityUniversity of Colorado, DenverAstraZenecaIntermountain Health CareMcMaster UniversityNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Temple University
University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,238 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this University of Pittsburgh page

1,238 registered trials is a research-attention snapshot, not an endorsement of University of Pittsburgh or any single study.

  • 160 of University of Pittsburgh's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Depression is the condition University of Pittsburgh studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Pittsburgh pipeline card: 1,238 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.