University of Pittsburgh

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Pittsburgh sits in the top decile of US sponsors by registered trial count (#22 of 15,742 sponsors by registered trial count).

1,238 total trials 160 currently recruiting 917 completed early-phase tilt top decile by trial count

University of Pittsburgh: 1,238 sponsored US clinical trials, 160 recruiting.

University of Pittsburgh sponsors 1,238 registered US clinical trials on ClinicalTrials.gov, 160 of them currently recruiting, and 917 completed. 84 of these trials are in Phase 3-4 (later-stage) and 160 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 17 trials.

Top-decile sponsor footprint

University of Pittsburgh ranks in the top decile of sponsors by registered trial count (#22 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 66/100

917 of 1,014 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,238 total, page 24 of 25

TERMINATED Phase 4

IVIG Versus Placebo for the Treatment of Patients With Severe C-Diff

NCT00177970

COMPLETED

Epidemiology of Coronary Heart Disease in Men Aged 40 and Over

NCT00069797

COMPLETED Phase 1

Safety Study of S-CKD602 in Patients With Advanced Malignancies

NCT00177281

COMPLETED

Development of Early Detection Signs for Gastrointestinal Cancer

NCT00633334

COMPLETED

Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus

NCT00222807

COMPLETED NA

Effectiveness of Depression Treatment Following Coronary Artery Bypass Surgery

NCT00091962

COMPLETED

Donors After Cardiac Death: Validating Identification Criteria

NCT00177606

COMPLETED Phase 4

Improving Symptoms of Schizophrenia and Schizoaffective Disorder by Supplementing Medications With Pravastatin

NCT00177580

COMPLETED NA

Early Recovery Adherence Therapy for Bipolar Alcoholics

NCT00167323

COMPLETED Phase 1

Evaluation of Alternative Exercise Treatments on Weight Loss in Overweight Women.

NCT00177632

COMPLETED NA

Agewise Project 3: Brief Behavioral Treatment of Insomnia in Primary Care

NCT00177203

COMPLETED Phase 4

Treatment of Depression in Adults

NCT00073697

COMPLETED NA

The Prevention of Osteoporosis in Premenopausal and Newly Postmenopausal (Up to 8 Years) Women With Breast Cancer Following Chemotherapy (REBBeCA Study)

NCT00118508

COMPLETED Phase 4

Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke

NCT00227994

COMPLETED Phase 4

Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children

NCT00245193

COMPLETED NA

The S.A.F.E. Study : Computer-Aided Counseling to Prevent Teen Pregnancy/Sexually Transmitted Diseases (STDs)

NCT00151151

COMPLETED Phase 1

Effect of Exercise on Prevention of Weight Gain

NCT00177502

COMPLETED NA

Web-based Support for People With Schizophrenia and Their Families

NCT00177983

COMPLETED Phase 2

Treatment of Schizophrenia Through Internet-Based Psychoeducation

NCT00051233

COMPLETED

Multi-Tracer PET Quantitation of Insulin Action in Muscle (Phase 1, Phase 2, Phase 3, Phase 4)

NCT00222885

COMPLETED Phase 1

Therapy for Depression With Co-occurring Panic or Anxiety Symptoms

NCT00051207

COMPLETED Phase 2

Donepezil HCl & Cognitive Deficits in Autism

NCT00047697

COMPLETED NA

Promoting Health in People With Fibromyalgia

NCT00167271

COMPLETED NA

Treatment of Depressed Adolescents With Physical Illness

NCT00446238

COMPLETED Phase 2

Health Interventions for Survivors and Primary Support Persons of Spinal Cord Injury

NCT00148239

COMPLETED NA

Cognitive/Cerebrovascular Consequences of HTN Treatment

NCT00151138

COMPLETED

Genetics of Middle Ear Disease

NCT00422136

COMPLETED

In Vitro Evaluation of Immune Responses in Cutaneous T-Cell Lymphoma (CTCL)

NCT00177190

COMPLETED NA

Coordinated Endoscopic Colorectal Cancer Screening

NCT00327457

COMPLETED NA

Coordinating Center for Caregiver Intervention Trial

NCT00177489

COMPLETED NA

A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen

NCT00427661

COMPLETED NA

Enhancing Tobacco Abstinence Following Hospitalization

NCT00222703

COMPLETED Phase 3

Prevention of Osteoporosis in Men With Prostate Cancer on Androgen Deprivation Therapy (POP Study)

NCT00177619

COMPLETED Phase 4

Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study

NCT00222820

COMPLETED Phase 1

Inhaled Bicarbonate Therapy in Cystic Fibrosis

NCT00177645

COMPLETED Phase 4

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

NCT00177216

COMPLETED NA

Preference and Vegetarian Diet in Weight Loss Treatment

NCT00330629

COMPLETED Phase 4

Pharmacotherapy in Depression With Panic Spectrum

NCT00177996

COMPLETED Phase 2

Reduction of Triglycerides in Women on Hormone Replacement Therapy

NCT00023543

COMPLETED Phase 2

Calcitriol and Dexamethasone in Patients With Myelodysplastic Syndromes

NCT00030069

COMPLETED Phase 4

Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study

NCT00177567

COMPLETED Phase 2

Pharmacological Intervention Project (Fluoxetine)

NCT00027378

COMPLETED

Low Dose Irradiation for Small Bowel Transplant

NCT00382486

COMPLETED Phase 4

Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction

NCT00022854

COMPLETED Phase 2

Treatment of SSRI-Resistant Depression In Adolescents (TORDIA)

NCT00018902

COMPLETED Phase 1

Low-Dose Radiation to Prevent Complications of Back Surgery

NCT00018876

COMPLETED Phase 4

Safety and Efficacy of Venlafaxine XR in Elderly Patients With Major Depression

NCT00177528

COMPLETED

Molecular Associations With Reproductive Failure

NCT00298116

COMPLETED Phase 3

Surgical Versus Nonsurgical Treatment for Spinal Stenosis

NCT00022776

COMPLETED Phase 1

Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders

NCT00600470

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Phase Distribution

PhaseTrial count
Phase 1 81
Phase 2 79
Phase 3 28
Phase 4 56

What is open in the University of Pittsburgh pipeline

160 recruiting of 1,238 indexed (13% open); 917 completed (74%).

Phase mix: 84 late (III/IV) vs 160 early (I/II) (early-phase heavy).

Top condition: Depression (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Pittsburgh: open-pipeline peers nationwide

Peers matched on 1,238 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 12%14%16%18%20%22% Total trials Recruiting share University of PittsburghNorthwestern UniversityEmory UniversityUniversity of Colorado, DenverAstraZenecaIntermountain Health CareMcMaster UniversityNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Temple University
University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Pittsburgh sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,238 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this University of Pittsburgh page

1,238 registered trials is a research-attention snapshot, not an endorsement of University of Pittsburgh or any single study.

  • 160 of University of Pittsburgh's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Depression is the condition University of Pittsburgh studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Pittsburgh pipeline card: 1,238 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.