Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00178035 · ClinicalTrials.gov registry record · Phase 4
Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals
A Phase 4 study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 4
- Development phase
- 158
- Enrollment target
NCT00178035: Completed Phase 4 study, sponsored by University of Pittsburgh.
NCT00178035 is a Phase 4 study that has completed, run by University of Pittsburgh. The registered enrollment target is 158 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (69% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00178035, a Phase 4 study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 158 participants
- Enrollment target
Study Summary
This study will determine the effectiveness of total sleep deprivation (TSD) for one night plus paroxetine versus either TSD plus placebo or paroxetine alone in inducing rapid symptom resolution of major depression in the elderly.
Interventions
- DRUG paroxetine
- BEHAVIORAL One night of Total Sleep Deprivation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 158 participants |
| Start Date | 1999-12 |
| Est. Completion | 2003-08 |
| Phase | Phase 4 |
What the finished NCT00178035 record still lists
NCT00178035 is an interventional study that assigns participants to a tested intervention. The registered 158 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (69% lower).
The record links to 0 conditions, and to 2 interventions - of which paroxetine is the first listed.
NCT00178035 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00178035 about?
NCT00178035 is a clinical study titled "Sleep Deprivation Plus Paroxetine for Treating Major Depression in Elderly Individuals". This study will determine the effectiveness of total sleep deprivation (TSD) for one night plus paroxetine versus either TSD plus placebo or paroxetine alone in inducing rapid symptom resolution of major depression in the elderly.
What is the current status of trial NCT00178035?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 158 participants. The study started on 1999-12. Estimated completion is 2003-08.
What interventions are being tested in trial NCT00178035?
The interventions under investigation include: paroxetine (DRUG), One night of Total Sleep Deprivation (BEHAVIORAL).
Who is sponsoring clinical trial NCT00178035?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00178035's enrollment target sits among peer trials
158 516th of 2000 higher than 1,482 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04486833 · 158 participants · Phase 1
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
- NCT04697966 · 158 participants · NA
Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
- NCT04969835 · 158 participants · Phase 1
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
- NCT05230732 · 158 participants · NA
Neuromodulation of Inflammation and Endothelial Function
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia