University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 6 of 23

COMPLETED NA

PHARM-S.A.V.E.S: Suicide Prevention Training

NCT05128227

COMPLETED

Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary Dyskinesia

NCT05161858

TERMINATED Phase 2

Efficacy of Liraglutide Therapy in Patients With IPAA

NCT04763564

COMPLETED NA

Ultrabrief Behavioral Activation for Reducing Alcohol Use

NCT05086172

COMPLETED NA

Improving Appetite Regulation in Patients With Obesity

NCT05200520

COMPLETED NA

Digihaler in Chronic Obstructive Pulmonary Disease (COPD)

NCT05241288

COMPLETED Early Phase 1

Effects Zulresso on Postpartum Psychosis

NCT05314153

COMPLETED NA

Investigating Central Neurophysiologic Correlates of Non-Motor Symptoms of Parkinson's Disease

NCT05205772

COMPLETED NA

Theta Connectivity in Working Memory

NCT05204381

COMPLETED NA

Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2)

NCT05178173

COMPLETED NA

How to Get Started: Identifying the Critical Ingredients to Improve Gait Initiation in Parkinson Disease

NCT05625789

COMPLETED

Patterns of Natural Aging and the Role of Senescence Registry

NCT05123859

TERMINATED Phase 2

The Impact of Oxidative Stress on Erythrocyte Biology

NCT04028700

COMPLETED NA

"MyPlan" - Individualized Planned Eating Patterns for Adolescents With Type 1 Diabetes

NCT05147324

COMPLETED NA

RCT for Innovating Stress-related eHealth

NCT05305235

COMPLETED NA

Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia

NCT05084924

COMPLETED NA

Med-South Lifestyle Program Implementation Study

NCT05067816

COMPLETED NA

Developing and Evaluating Product Messaging

NCT04716010

COMPLETED NA

Healthy Food First

NCT05048836

COMPLETED NA

Alternative Dietary Approaches Online to Promote Tracking

NCT05049005

COMPLETED NA

Open Trial of a Behavioral Activation Telepsychology Intervention for People Who Inject Drugs

NCT04943432

COMPLETED Phase 4

Baseline Oral Health Study: UnCoVer the Connections to General Health

NCT04954313

COMPLETED NA

NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged, Unemployed Populations

NCT04815278

COMPLETED NA

Adapting Connect-Home Transitional Care for the Unique Needs of Persons With Alzheimer's Disease and Other Dementias and Their Caregivers

NCT05887388

COMPLETED NA

Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction

NCT07681193

TERMINATED Phase 2

Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)

NCT04186247

COMPLETED NA

Comparing KIM to TVT Exact Sling

NCT04985799

COMPLETED NA

Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention

NCT05007366

COMPLETED NA

Improving Employment Outcomes for Probationers With Mental Illnesses

NCT04948853

COMPLETED NA

Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion

NCT04906499

COMPLETED

Examining Changes in Nasal IL-1 During Acute Asthma Exacerbation in Adolescents

NCT04748055

COMPLETED NA

Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers

NCT04948866

COMPLETED NA

Animal Assisted Therapy in Dentistry

NCT04708028

COMPLETED NA

Evaluation of an Interdisciplinary Decision Guide for Infant Feeding Assessment

NCT04850794

COMPLETED Phase 1

Gut Butyrate and Blood Pressure in African Americans

NCT04415333

COMPLETED NA

Nalox-Comm: Naloxone Communication Training for Pharmacists

NCT04677387

COMPLETED Early Phase 1

Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype

NCT04901715

COMPLETED NA

Mechanism of Action of tACS for the Treatment of MDD

NCT03994081

COMPLETED

COVID-19 Antibody Levels After Vaccines

NCT04944134

COMPLETED

Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies

NCT04919018

COMPLETED NA

Engaging Families to Improve the Care of Patients With Hypospadias

NCT05056311

COMPLETED NA

RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?

NCT05210920

COMPLETED

Two is Better Than One: A Novel Venous Access System for Intermittent Apheresis

NCT04846374

COMPLETED NA

The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women

NCT04705779

COMPLETED NA

The TRAIN Study: A Concussion Prevention Strategy in Middle Schools

NCT04841473

COMPLETED Phase 1

A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome

NCT04278729

TERMINATED NA

Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon

NCT03951064

TERMINATED Phase 2

Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19

NCT04748783

COMPLETED

Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics

NCT04670627

COMPLETED NA

Place-based Mapping in EAS Listeners

NCT04722042

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.